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126054-77-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "126054-77-1" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N0237
CAS No.: 126054-77-1
Atractyloside A is an orally active inhibitor of the TLR4/MyD88/NF-κB signaling pathway and also an opener of the mitochondrial permeability transition pore (MPTP). Atractyloside A interferes with the activation of the TLR4/MyD88/NF-κB pathway, thereby inhibiting intestinal inflammatory responses. Atractyloside A reverses mucin synthesis impairment, improves intestinal barrier integrity, and restores homeostasis by altering the composition of the gut microbiota. Atractyloside A can be used in studies related to spleen deficiency diarrhea and myocardial injury .
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