3 Results for "

1316755-16-4

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "1316755-16-4" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-13106
CAS No.: 1316755-16-4
Purity:  98.89%
Synonyms: EMA401; PD-126055; (S)-EMA400
Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons .
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Cat. No.: HY-13106A
CAS No.: 1316755-17-5
Synonyms: EMA401 sodium; PD-126055 sodium
Target:  

Angiotensin Receptor

Research Areas:  

Neurological Disease Endocrinology

Olodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons .
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Cat. No.: HY-W742300
CAS No.: 6056-11-7
Synonyms: SKF 70230A hydrochloride; SQ 15874 hydrochloride; Pipazetate hydrochloride
Target:  

GABA Receptor

Research Areas:  

Inflammation/Immunology

Pipazethate (SKF 70230A; SQ 15874) hydrochloride is a potent GABA antagonist. Pipazethate hydrochloride shows antitussive activity and can be used in research in cough suppressant .
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