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Results for "

15(S)-HEPE

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-130675A
    15(S)-HEPE

    15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA

    		 Lipoxygenase Inflammation/Immunology
    15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma.
    15(S)-HEPE
  • HY-130675
    (±)15-HEPE

    (±)15-hydroxyeicosapentaenoic acid; 15-OHEPA

    		 Lipoxygenase Bacterial Metabolic Disease
    (±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE (HY-130675A). (±)15-HEPE is active against P. acnes and S. aureus (MICs = 128 and 512 mg/L, respectively). It inhibits aggregation of isolated rat neutrophils induced by the formyl peptide receptor agonist fMLP (IC50 = 4.7 µM). Bronchoalveolar lavage fluid (BALF) levels of (±)15-HEPE are increased in patients with allergic asthma or COVID-19.
    (±)15-HEPE
  • HY-130675AS
    15(S)-HEPE-d5

    		Isotope-Labeled Compounds Others
    15(S)-HEPE-d5 is the deuterium labeled 15(S)-HEPE .
    15(S)-HEPE-d5
  • HY-109089S
    Epeleuton-d5

    15(S)-HEPE-d5 ethyl ester; 15(S)-Hydoxy EPA-d5 ethyl ester; 15(S)-Hydoxy eicosapetaeoic acid-d5 ethyl ester

    		 Isotope-Labeled Compounds Others
    Epeleuton-d5 (15(S)-HEPE-d5 ethyl ester) is deuterium labeled Epeleuton. Epeleuton is a second-generation synthetic N-3 fatty acid derivative with activity in patients with non-alcoholic fatty liver disease, although it did not reach the primary endpoints of alanine aminotransferase and liver stiffness, but it can significantly reduce triglycerides, glycated hemoglobin, plasma glucose and inflammatory markers .
    Epeleuton-d5

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