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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
15-Hydroxyprostaglandin dehydrogenase
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "15-Hydroxyprostaglandin dehydrogenase" in MCE Product Catalog:
Cat. No.: HY-176803
CAS No.: 2673403-86-4
Target:
Research Areas:
MF-DH-300 is a 15-PGDH inhibitor that can be applicable to the research of muscle disorders such as spinal muscular atrophy (SMA).
Cat. No.: HY-117723
CAS No.: 452077-89-3
MF-PGDH-008 serves as an inhibitor of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) .
Cat. No.: HY-119973
CAS No.: 78028-01-0
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CAY10397 is a selective and orally active 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. CAY10397 can inhibit 15-PGDH-dependent endogenous metabolite production. CAY10397 blocks the selenium-dependent protective in inflammation. CAY10397 can be used for the research of colitis .
Cat. No.: HY-124230
CAS No.: 355827-05-3
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15-PGDH-IN-3 (Compound 61) is a selective competitive inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) .
Cat. No.: HY-178113
CAS No.: 1537192-10-1
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15-PGDH-IN-4 (Compound 40) is a 15-PGDH inhibitor with an IC50 of 1.2 nM against h15-PGDH. 15-PGDH-IN-4 functionally inhibits the activity of 15-PGDH. 15-PGDH-IN-4 can be used in the research of colitis .
Cat. No.: HY-116096
CAS No.: 20897-91-0
Synonyms: 15(R)-Prostaglandin E1; 15-Epiprostaglandin E1
15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1) is a stereoisomer of PGE1 (HY-B0131) but with less biological activity . 15-epi-PGE1 is a non-competitive inhibitor for human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 170 μM .
Cat. No.: HY-118465
CAS No.: 65085-69-0
Synonyms: ent-PGE2
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ent-Prostaglandin E2 (ent-PGE2) is an enantiomer of PGE2 (HY-101952). unlike PGE2, ent-PGE2 is a poor substrate for 15-hydroxyprostaglandin dehydrogenase .
Cat. No.: HY-E71195
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15-Hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) acts on prostaglandin E2, F2α and B1, but not on prostaglandin D2.
Cat. No.: HY-E71196
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15-Hydroxyprostaglandin dehydrogenase (NADP+) (EC 1.1.1.197) acts on prostaglandins E2, F2α and B1, but not on prostaglandin D2.
Cat. No.: HY-114695
CAS No.: 43042-79-1
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Prostaglandin F2α-1-glyceryl ester can be oxidized by 15-hydroxyprostaglandin dehydrogenase (15-HPGDH) .
Cat. No.: HY-E71197
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15-Hydroxyprostaglandin-D dehydrogenase (NADP+) (EC 1.1.1.196) is specific for prostaglandins D.
Cat. No.: HY-E71198
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15-Hydroxyprostaglandin-I dehydrogenase (NADP+) (EC 1.1.1.231) is specific for prostaglandin I2.
Cat. No.: HY-183651
CAS No.: 1714984-32-3
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15-PGDH-IN-5 is a sulfoxide-based inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH). 15-PGDH-IN-5 exhibits great water solubility, metabolic stability, and in vivo exposure levels. 15-PGDH-IN-5 blocks the 15-PGDH-mediated irreversible oxidative degradation of PGE2 and increases the effective concentration of endogenous PGE2 in tissues, thereby exerting anti-inflammatory effects and promoting tissue repair and regeneration. 15-PGDH-IN-5 is suitable for research into tissue injury and fibrosis-related diseases, such as inflammatory bowel disease and idiopathic pulmonary fibrosis .
Cat. No.: HY-174990A
CAS No.: 2927452-82-0
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HW201877 enantiomer is the enantiomer of HW201877 (HY-174990) and is 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor with an IC50 of 12.2 nM. HW201877 enantiomer can be used for the research of inflammatory bowel disease, idiopathic pulmonary fibrosis, ulcerative colitis, and Crohn's disease .
Cat. No.: HY-P70297
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HPGD; Hydroxyprostaglandin dehydrogenase 15-(NAD); 15-Hydroxyprostaglandin dehydrogenase; 15-PGDH; SDR36C1; PGDH1; 15-Hydroxyprostaglandin dehydrogenase [NAD(+)]; Short Chain dehydrogenase/Reductase Family 36C, Member 1; Prostaglandin dehydrogenase 1; NAD+-Dependent 15-Hydroxyprostaglandin dehydrogenase; Short Chain dehydrogenase/Reductase Family 36C Member 1; Eicosanoid/Docosanoid dehydrogenase; 15-Hydroxyprostaglandin dehydrogenase (NAD(+)); PHOAR1; Eicosanoid/Docosanoid dehydrogenase [NAD(+)]; PGDH
Species:
Human
Source:
HEK293
Cat. No.: HY-E71717B
Target:
Research Areas:
3α-Hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) acts on androsterone and other 3α-hydroxysteroids and on 9-, 11- and 15-hydroxyprostaglandin.
Cat. No.: HY-P75555
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HPGD; Hydroxyprostaglandin dehydrogenase 15-(NAD); 15-Hydroxyprostaglandin dehydrogenase; 15-PGDH; SDR36C1; PGDH1; 15-Hydroxyprostaglandin dehydrogenase [NAD(+)]; Short Chain dehydrogenase/Reductase Family 36C, Member 1; Prostaglandin dehydrogenase 1; NAD
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P75547A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HPGD; Hydroxyprostaglandin dehydrogenase 15-(NAD); 15-Hydroxyprostaglandin dehydrogenase; 15-PGDH; SDR36C1; PGDH1; 15-Hydroxyprostaglandin dehydrogenase [NAD(+)]; Short Chain dehydrogenase/Reductase Family 36C, Member 1; Prostaglandin dehydrogenase 1; NAD
Species:
Human
Source:
E. coli
Cat. No.: HY-P87947
Synonyms: PGDH1, SDR36C1, HPGD, 15-Hydroxyprostaglandin dehydrogenase [NAD(+)], 15-PGDH, Eicosanoid/docosanoid dehydrogenase [NAD(+)], Prostaglandin dehydrogenase 1, Short chain dehydrogenase/reductase family 36C member 1
Cat. No.: HY-P80590
Synonyms: 15 Hydroxyprostaglandin dehydrogenase [NADP ]; 15-Hydroxyprostaglandin dehydrogenase [NADP ]; Carbonyl reductase [NADPH] 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9 ketoreduc
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
