78028-01-0
78028-01-0
Chemical Structure
CAY10397
- CAS No.: 78028-01-0
- Formula:C17H16N2O5
- Molecular Weight:328.32
IUPAC Name: (E)-2-(5-((4-(ethoxycarbonyl)phenyl)diazenyl)-2-hydroxyphenyl)acetic acid
InChIKey: YYBSDOZYJSGLTH-VHEBQXMUSA-N
SMILES: OC1=C(C=C(C=C1)/N=N/C2=CC=C(C=C2)C(OCC)=O)CC(O)=O
Biological Activity: CAY10397 is a selective and orally active 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. CAY10397 can inhibit 15-PGDH-dependent endogenous metabolite production. CAY10397 blocks the selenium-dependent protective in inflammation. CAY10397 can be used for the research of colitis[1][2].
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CAY10397 | CAY10397 is a selective and orally active 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. CAY10397 can inhibit 15-PGDH-dependent endogenous metabolite production. CAY10397 blocks the selenium-dependent protective in inflammation. CAY10397 can be used for the research of colitis. | |||||||||||||||||||||
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References
- [1]. Liu X, et al. 11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid. Chem Res Toxicol. 2011;24(12):2227-2236. [Content Brief]
- [2]. Kaushal N, et al. Crucial role of macrophage selenoproteins in experimental colitis. J Immunol. 2014;193(7):3683-3692. [Content Brief]
