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1829524-73-3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (5) Liposome (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (1)
Oligonucleotides:	Pegylated Lipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-168374

DSPE-PEG2000-Mannose 1 Publications Verification	Biochemical Assay Reagents Liposome Small Interfering RNA (siRNA)	Cancer
DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume .

HY-168374A

DSPE-PEG1000-Mannose	Biochemical Assay Reagents	Others
DSPE-PEG1000-mannose is an amphiphilic molecule that can be used to synthesize lipid nanoparticles .

HY-168374D

DSPE-PEG10000-Mannose	Biochemical Assay Reagents	Others
DSPE-PEG10000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG10000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.

HY-168374B

DSPE-PEG5000-Mannose	Biochemical Assay Reagents	Others
DSPE-PEG5000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG5000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.

HY-168374C

DSPE-PEG3400-Mannose	Biochemical Assay Reagents	Others
DSPE-PEG3400-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG3400-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.

Cat. No.	Product Name	Type

HY-168374A

DSPE-PEG1000-Mannose	Biochemical Assay Reagents
DSPE-PEG1000-mannose is an amphiphilic molecule that can be used to synthesize lipid nanoparticles .

HY-168374D

DSPE-PEG10000-Mannose	Biochemical Assay Reagents
DSPE-PEG10000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG10000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.

HY-168374B

DSPE-PEG5000-Mannose	Biochemical Assay Reagents
DSPE-PEG5000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG5000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.

HY-168374C

DSPE-PEG3400-Mannose	Biochemical Assay Reagents
DSPE-PEG3400-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG3400-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.

Cat. No.	Product Name		Classification

HY-168374

DSPE-PEG2000-Mannose 1 Publications Verification		Pegylated Lipids
DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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