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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
20-5,14-HEDE-d2-1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "20-5,14-HEDE-d2-1" in MCE Product Catalog:
Cat. No.: HY-160099S1
Synonyms: WIT003-d2-1
2
Target:
Research Areas:
20-HEDE (WIT 002) is an antagonist of 20-hydroxyeicosatetraenoic acid (20-HETE).
Cat. No.: HY-160099
CAS No.: 240427-86-5
Synonyms: WIT003
Research Areas:
20-5,14-HEDE (WIT003) is an analog of 20-HETE. 20-5,14-HEDE activates PI3K/Akt signaling pathway, thereby exhibiting anti-apoptotic and cell survival promoting effects. 20-5,14-HEDE is the agonist for 20-HETE that increases intracellular Ca 2+ concentrations, thereby enhancing vasoconstriction .
Cat. No.: HY-121987A
CAS No.: 77159-57-0
Target:
Research Areas:
(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).
Cat. No.: HY-121987
CAS No.: 92693-04-4
Target:
Research Areas:
15(S)-HEDE (Compound 8) is an analogue of 15-HEDE (HY-121987A) that inhibits 5-lipoxygenase with an IC50 value of 26 μM. 15(S)-HEDE is promising for research of inflammatory disease .
Cat. No.: HY-130310A
CAS No.: 330800-90-3
Target:
Research Areas:
11(S)-HEDE is isolated by the chromatographic resolution of 11(S)-HEDE. There are no reports of biological activity associated with 11(S)-HEDE in the literature.
Cat. No.: HY-130310B
CAS No.: 5598-37-8
Synonyms: 11-hydroxy-12,14-Eicosadienoic acid
Target:
Research Areas:
(±)11-HEDE is a racemic mixture of the monohydroxy fatty acids 11(S)-HEDE and 11(R)-HEDE. 11-HEDE is formed from eicosadienoic acid by cyclooxygenase (COX) and in macrophages.
Cat. No.: HY-130310
CAS No.: 330800-88-9
Target:
Research Areas:
11(R)-HEDE is produced from 11Z,14Z-eicosadienoic acid by COX in a lipoxygenase-type reaction.1 Spectrophotometric measurement of the conjugated diene absorbance of 11(R)-HEDE is occasionally used to quantify COX activity.
Cat. No.: HY-160099S
Synonyms: WIT003-d2
Cat. No.: HY-160099S2
Synonyms: WIT003-d2-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
