1 Result for "

2361115-35-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2361115-35-5" in MCE Product Catalog:

Cat. No.: HY-135312
CAS No.: 2361115-35-5
Purity:  98.13%
Research Areas:  

Cancer

AZ'6421 is an orally active ERα PROTAC degrader with a DC50 of 0.4 nM. AZ'6421 recruits the VHL E3 ligase to form a ternary complex, inducing proteasome-mediated polyubiquitination and degradation of ERα. AZ'6421 inhibits the growth of ER + cancer cells. AZ'6421 can be used in studies related to ER + breast cancer .
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