1 Result for "

2387570-00-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2387570-00-3" in MCE Product Catalog:

Cat. No.: HY-155079
CAS No.: 2387570-00-3
Purity:  98.31%
Target:  

EGFR

Research Areas:  

Neurological Disease Cancer

DZD1516 is an orally active, reversible, blood-brain barrier (BBB)-penetrant selective HER2 tyrosine kinase inhibitor with an IC50 of 0.56 nM against HER2. DZD1516 is not a substrate of P-gp or BCRP, and exhibits high passive permeability. DZD1516 inhibits tumor growth in HER2-positive brain metastasis, leptomeningeal metastasis and subcutaneous xenograft models, and can be used for research related to HER2-positive breast cancer and central nervous system metastasis .
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