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2891469-80-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2891469-80-8" in MCE Product Catalog:

Cat. No.: HY-P3346
CAS No.: 2891469-80-8
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cardiovascular Disease

NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) (compound 39) is a potent APJ agonist, with a Ki of 0.6 nM. NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) can activate Gαi1 (EC50=0.8 nM) and recruit β-arrestin2 (EC50=31 nM). NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) exhibits prolonged cardiac effects .
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