1 Result for "

3064731-00-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3064731-00-3" in MCE Product Catalog:

Cat. No.: HY-176456
CAS No.: 3064731-00-3
Target:  

PARP

Research Areas:  

Inflammation/Immunology Cancer

PARP14 inhibitor 2 (Compound 3) is an orally active and highly selective PARP14 inhibitor with an IC50 value of <30 nM. PARP14 inhibitor 2 inhibits the mono-ADP-ribosyltransferase activity of PARP14 and regulates IFN-γ and IL-4 signaling, reversing protumor macrophage polarization and inhibiting anti-tumor inflammatory responses. PARP14 inhibitor 2 is promising for research of PARP14-related diseases such as tumors, atopic dermatitis and autoimmune diseases .
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