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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
5-hydroxytryptamine 2A receptor
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "5-hydroxytryptamine 2A receptor" in MCE Product Catalog:
2
Category:
Xanthones Guttiferae Metabolic Disease Garcinia mangostana Linn. Phenols Polyphenols Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-A0019A
CAS No.: 199739-10-1
Synonyms: 9-Hydroxyrisperidone palmitate
Target:
Research Areas:
Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia .
Cat. No.: HY-169841
CAS No.: 2957888-70-7
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Research Areas:
IHCH-7086 is a blood-brain barrier-permeable, partial β-arrestin-biased agonist of 5-HT2AR with a Ki of 12.59 nM. IHCH-7086 blocks D-lysergic acid diethylamide-induced head-twitch response in mice and alleviates depression-like behaviors in mice subjected to acute restraint stress or injected with Corticosterone (HY-B1618). IHCH-7086 is applicable to research related to depression .
Cat. No.: HY-A0019AS
CAS No.: 1794685-21-4
Synonyms: 9-Hydroxyrisperidone palmitate-d4
Cat. No.: HY-13051
CAS No.: 630407-66-8
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Research Areas:
SB-773812 is a moderate-affinity antagonist at dopamine receptor 2 (pKi=7.4) and a high-affinity antagonist at the dopamine receptor 3 (pKi=8.5) and at the serotonin 5-hydroxytryptamine receptors 2A (pKi=9.0), 2C (pKi=8.1), and 6 (pKi=8.1). SB-773812 is promising for research of central nervous system disorders .
Cat. No.: HY-W1123900
CAS No.: 2945111-66-8
Target:
Research Areas:
5-HT2A agonist 3 (Compound P-141) is a selective 5-hydroxytryptamine 2A receptor (5-HT2A) agonist with an EC50 value of 13.80 nM. 5-HT2A agonist 3 is promising for research of mental illnesses such as depression, post-traumatic stress disorder, obsessive-compulsive disorder, and central nervous system disorders .
Cat. No.: HY-175285
CAS No.: 780703-57-3
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Research Areas:
5-HT2AR-IN-1 (Compound Ie) is an orally active 5-hydroxytryptamine 2A receptor (5-HT2AR) inhibitor with antidepressant efficacy. 5-HT2AR-IN-1 reduces 5-HT2AR expression and SERT protein levels. 5-HT2AR-IN-1 is promising for research of central nervous system (CNS), such as depression and addiction-related disorders .
Cat. No.: HY-165527
CAS No.: 200398-40-9
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Research Areas:
S18327 is a multi-target antipsychotic agent. S18327 exerts its efficacy by acting on multiple neurotransmitter systems in the brain, and it has antagonistic effects on dopamine receptors (particularly the D2 receptor) and 5-hydroxytryptamine 2A receptors (5-HT2A receptor). S18327 can counteract excessive dopamine activity and hypo-function of glutamate. S18327 exhibits a multi-parameter pharmacological profile that is highly similar to that of Clozapine (HY-14539). S18327 can produce the same discriminative stimulus as Clozapine, improve cognitive filtering deficits associated with schizophrenia, and display anxiolytic properties. S18327 has relatively weak affinity for histaminergic receptors and muscarinic receptors, which avoids the side effects of Clozapine .
Cat. No.: HY-N1957R
CAS No.: 31271-07-5
Synonyms: γ-Mangostin (Standard)
Cat. No.: HY-A0019AR
CAS No.: 199739-10-1
Synonyms: 9-Hydroxyrisperidone palmitate (Standard)
Research Areas:
Paliperidone palmitate (Standard) is the analytical standard of Paliperidone palmitate. This product is intended for research and analytical applications. Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia .
Cat. No.: HY-P703149
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; Serotonin receptor 2A; Prev. HTR2; Serotonin 5-HT-2A receptor; 5-HT2A; 5-HT2 receptor; 5-hydroxytryptamine (Serotonin) receptor 2A, G Protein-Coupled; 5-HT-2A; 5-hydroxytryptamine (Serotonin) receptor 2A; 5-hydroxytryptamine receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703150
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; Serotonin receptor 2A; Prev. HTR2; Serotonin 5-HT-2A receptor; 5-HT2A; 5-HT2 receptor; 5-hydroxytryptamine (Serotonin) receptor 2A, G Protein-Coupled; 5-HT-2A; 5-hydroxytryptamine (Serotonin) receptor 2A; 5-hydroxytryptamine receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P810892
Synonyms: HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
