2 Results for "

AANAT inhibitors

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AANAT inhibitors" in MCE Product Catalog:

Cat. No.: HY-157521
CAS No.: 3055162-52-9
Target:  

Acyltransferase

AANAT-IN-1 is an arylalkylamine N-acetyltransferase (AANAT) inhibitor with a sheep AANAT IC50 of 9.9 μM. AANAT-IN-1 binds to the active site of sheep AANAT, interacting with amino acid residues via hydrogen bonds, hydrophobic interactions, ionic interactions, and water bridges, inhibiting the enzyme's catalytic activity. AANAT-IN-1 can be used for the researches of circadian rhythm-associated neuropsychiatric conditions, seasonal affective disorder, and other diseases associated with abnormally elevated melatonin levels .
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Cat. No.: HY-179397
Target:  

Acyltransferase

Research Areas:  

Neurological Disease

AANAT-IN-2 (Compound 5g) is a potent and selective AANAT inhibitor, with an IC50 of 1.1 μM. AANAT-IN-2 can be used for the study of seasonal affective disorder (SAD) .
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