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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
AR1 receptor
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "AR1 receptor" in MCE Product Catalog:
9
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5
5 Cited Publications
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JPE-1375 is a complement C5a receptor 1 (C5aR1) antagonist. JPE-1375 effectively inhibits polymorphonuclear leukocyte mobilization (EC50=6.9 μM) and reduces TNF levels (EC50=4.5 μM) in mice. JPE-1375 can be used in studies of autoimmune and inflammatory diseases .
4
Category:
Simaroubaceae Ailanthus altissima (Mill.) Swingle Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology
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2
2 Cited Publications
Cat. No.: HY-P1345A
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1
1
Cat. No.: HY-P99450
CAS No.: 2226393-85-5
Synonyms: IPH 5401; Anti-C5AR1 mAb
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Cat. No.: HY-P1345
CAS No.: 869988-94-3
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Cat. No.: HY-N0138S
CAS No.: 117490-40-1
Synonyms: 3,7-Dimethylxanthine-d6
Cat. No.: HY-W140282
CAS No.: 121379-63-3
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ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 (HY-130492) to degrade AR .
Cat. No.: HY-177094
CAS No.: 2489430-53-5
Synonyms: INF056
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Izicopan (INF056) is a complement factor C5a receptor (C5aR1) antagonist. Izicopan inhibits C5a-induced calcium mobilization with an IC50 of 10-100 nM. Izicopan is applicable for the research of complement-mediated inflammatory responses .
Cat. No.: HY-W130878
CAS No.: 1806-26-4
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4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the C3a/C3aR axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg)/Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR))/IκBα/NF-κB pathway .
Cat. No.: HY-163378
CAS No.: 2365325-67-1
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C5aR1 antagonist 1 (Compound 7e) is an orally active C5a receptor 1 (C5aR1) antagonist. C5aR1 antagonist 1 is active in DISCO and migration assays, with IC50 values of 38 nM and 17 nM, respectively. C5aR1 antagonist 1 can be used for the research of acute and chronic inflammatory diseases .
Cat. No.: HY-163379
CAS No.: 2365161-92-6
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C5aR1 antagonist 2 (Compound 6a) is an orally active C5a receptor 1 (C5aR1) antagonist that shows efficacy in inhibiting the C5a-induced neutrophil count increase. C5aR1 antagonist 2 is potent in the DISCO and migration assays, with IC50 values of 21 and 3 nM, respectively. C5aR1 antagonist 2 can be used for the research of acute and chronic inflammatory diseases .
Cat. No.: HY-176714
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VUF26034 (Compound 12b) is a photoresponsive ligand for the human β2-adrenergic receptor (β2-AR .
Cat. No.: HY-124259
CAS No.: 152918-27-9
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I-AB-MECA is an important radioligand for the study of A3 adenosine receptors (A3AR) .
Cat. No.: HY-P5509
CAS No.: 230968-98-6
Cat. No.: HY-P700398
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: C5AR1; C5a-R; Prev. C5R1; C5a Anaphylatoxin Chemotactic receptor; C5AR; C5a Anaphylatoxin receptor; CD88; CD88 Antigen; C5A; C5a Ligand; C5a Anaphylatoxin Chemotactic receptor 1; C5AR; Complement Component 5a receptor 1; Complement C5a receptor 1; Complem
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
