1973408-76-2
1973408-76-2
Chemical Structure
ABM-14
- CAS No.: 1973408-76-2
- Formula:C25H18F3N3O2S
- Molecular Weight:481.49
IUPAC Name: 4-(3-(4'-hydroxy-[1,1'-biphenyl]-4-yl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
InChIKey: WVKLCXDKHAOSGV-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(N(C(N(C2=CC=C(C3=CC=C(O)C=C3)C=C2)C4(C)C)=S)C4=O)C=C1C(F)(F)F
Biological Activity: ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 (HY-130492) to degrade AR[1].
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ABM-14 | 98.10% | ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 (HY-130492) to degrade AR. | ||||||||||||||||||||
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References
Keywords
