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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Acetate kinase (ACK)
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Acetate kinase (ACK)" in MCE Product Catalog:
Research Areas:
Acetate kinase (ACK) is an enzyme widely distributed in bacteria and archaea. In the presence of ATP and divalent cations, it catalyzes the phosphorylation of acetate and promotes the production of acetyl-CoA. Often used in biochemical research .
6
6 Publications Verification
Research Areas:
ASP3026 is a selective and orally active inhibitor of anaplastic lymphoma kinase (ALK). ASP3026 is a selective and oral active anaplastic lymphoma kinase (ALK) inhibitor with a IC50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R, STAT3, AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP. It also inhibited ROS and ACK. ASP3026 can be used in anti-tumor research .
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4 Cited Publications
AIM-100 is a potent and selective Ack1 inhibitor with an IC50 of 21.58 nM. AIM-100 also inhibits Tyr 267 phosphorylation. AIM-100 does not inhibits other kinases including PI3-kinase and AKT subfamily members. AIM-100 has an anticancer effect .
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2 Cited Publications
GNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-Abl WT and Bcr-Abl T315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies .
(R)-9b is a potent inhibitor of ACK1 tyrosine kinase (IC50=56 nM) with anticancer activity. (R)-9b exhibits selectivity for ACK1 but has inhibitory effects on JAK family kinases JAK2 and Tyk2. (R)-9b can be used in the study of hormone-regulated cancers such as prostate and breast cancer .
Cat. No.: HY-149989
CAS No.: 2924415-92-7
Ack1 inhibitor 1 is a potent, selective, and orally active inhibitor of ACK1 kinase with an IC50 value of 2.1 nM. Ack1 inhibitor 1 inhibits the phosphorylation of ACK1 and activation of downstream AKT. Ack1 inhibitor 1 has anti-tumor activity .
Cat. No.: HY-E70868
Thirty-eight-negative kinase-1 (TNK1) is a member of the ACK family of NRTKs, which includes only two human kinases, TNK1 and TNK2 (also called ACK1). TNK1 Recombinant Human Active Protein Kinase is a recombinant TNK1 protein that can be used to study TNK1-related functions .
Cat. No.: HY-13326R
CAS No.: 1097917-15-1
Research Areas:
ASP3026 (Standard) is the analytical standard of ASP3026. This product is intended for research and analytical applications. ASP3026 is a selective and orally active inhibitor of anaplastic lymphoma kinase (ALK). ASP3026 is a selective and oral active anaplastic lymphoma kinase (ALK) inhibitor with a IC50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R, STAT3, AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP. It also inhibited ROS and ACK. ASP3026 can be used in anti-tumor research .
Cat. No.: HY-P75542
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TNK2; ACK; Tyrosine kinase Non Receptor 2; Activated Cdc42-Associated kinase 1; ACK1; ACK-1; Tyrosine kinase Non-Receptor Protein 2; Non-Specific Protein-Tyrosine kinase; Activated CDC42 kinase 1; Tyrosine kinase, Non-Receptor, 2; P21cdc42Hs; Activated P2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703058
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Acetate kinase; EC:2.7.2.1; Acetokinase; ackA; ack; b2296; JW2293
Species:
Others
Source:
E. coli
Cat. No.: HY-P703059
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Acetate kinase; EC:2.7.2.1; Acetokinase; ackA; ack; b2296; JW2293
Species:
Others
Source:
E. coli
Cat. No.: HY-10943R
CAS No.: 839706-07-9
Target:
Research Areas:
GNF-7 (Standard) is the analytical standard of GNF-7 (HY-10943). This product is intended for research and analytical applications. GNF-7 is a multiKinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-AblWT and Bcr-AblT315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 Kinase 1) and GCK (germinal center Kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
