7 Results for "

Ada protein

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Ada protein" in MCE Product Catalog:

Cat. No.: HY-N7368
CAS No.: 55366-56-8
Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
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Cat. No.: HY-N7368R
CAS No.: 55366-56-8
Hibifolin (Standard) is the analytical standard of Hibifolin. This product is intended for research and analytical applications. Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
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Cat. No.: HY-P74429
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ada; Adenosine Aminohydrolase; Adenosine Deaminase; Mutant Adenosine Deaminase; Ada1
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-180366
CAS No.: 5536-30-1
Research Areas:  

Others

5-Amino-2'-deoxyuridine is a thymidine analogue and substrate for chemical reaction. 5-Amino-2'-deoxyuridine can be use in the preparation of labeled probes for DNA microarray analysis .
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Cat. No.: HY-181065
CAS No.: 3099617-79-2
Research Areas:  

Cancer

LS-170 is a YEATS2 YEATS domain inhibitor with an IC50 of 0.14 μM. LS-170 displays selectivity for the YEATS2 YEATS domain over other YEATS domain family members and other epigenetic 'reader' and 'eraser' proteins. LS-170 reduces chromatin occupancy of the Ada-two-A-containing (ATAC) complex, decreases ATAC-dependent histone acetylation levels, and downregulates expression of ATAC-governed genes. LS-170 suppresses tumor growth in a lung cancer mouse model. LS-170 can be used for the research of non-small cell lung cancer .
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Cat. No.: HY-P705550
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KAT14; CSRP2-Binding protein; Prev. CSRP2BP; Cysteine Rich protein 2 Binding protein; CRP2BP; ATAC Component 2 Homolog (Drosophila); ATAC2; ATAC Component 2 Homolog; Cysteine-Rich protein 2-Binding protein; CSRP2 Binding protein; Ada2A-Containing Complex
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P76250
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ada2; Cat Eye Syndrome Chromosome Region, Candidate 1; Prev. CECR1; Adenosine Deaminase; Prev. IDGFL; SNEDS; ADGF; VAIHS; Cat Eye Syndrome Critical Region protein 1; PAN; Adenosine Deaminase 2; Adenosine Deaminase CECR1
Species:  
Human
Source:  
Sf9 insect cells
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