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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Ai9 reporter mice
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Ai9 reporter mice" in MCE Product Catalog:
Cat. No.: HY-185985
CAS No.: 3113145-60-8
Target:
Research Areas:
Am-Ka12K4 is a weakly positively charged peptide-based ionizable lipid. Am-Ka12K4 induces membrane disruption under endosomal pH conditions and possesses high lipid fusion capacity. Am-Ka12K4 forms tightly packed, stable lipid nanoparticles. Am-Ka12K4 mediates in vivo mRNA delivery, exhibits inherent liver tropism, and can be modified to adjust organ tropism, enabling selective mRNA delivery to the spleen, lung, or thymus. Am-Ka12K4 is applicable to research related to repetitive mild traumatic brain injury .
Cat. No.: HY-185984
Target:
Research Areas:
a12k4E-Ca is a C-terminal glutamate-modified peptidogenic ionizable lipid that can be used for the preparation of lipid nanoparticles (LNPs). a12k4E-Ca preferentially accumulates in the spleen in vivo, acts as a carrier to mediate spleen-selective mRNA delivery, and enables spleen-specific Cre recombinase-mediated gene editing. a12k4E-Ca restores serum biochemical parameters and cytokines/chemokines. a12k4E-Ca can be used in studies related to LNP preparation .
Cat. No.: HY-185751
CAS No.: 2760467-77-2
10A1P16 is an ionizable phospholipid composed of a tertiary amine, a phosphate group and three hydrophobic tails. As a spleen-selective RNA delivery vector, 10A1P16 successfully transfects approximately 30% of splenic macrophages and 6% of splenic B cells in vivo. 10A1P16 can be used to prepare spleen-selective 10A1P16-MDOA lipid nanoparticles, which effectively mediate mRNA delivery and gene editing in mouse models. This delivery system retains potent spleen-targeted mRNA delivery efficacy and can be applied to ovarian cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
