3 Results for "

Albumin paclitaxel

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Albumin paclitaxel" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-P99974
Synonyms: Nanoparticle Albumin-bound paclitaxel; Nanoparticle Albumin-bound ABI-007

Research Areas:  

Cancer

Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel, in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability. Nab-Paclitaxel displays less toxicity and greater antitumor activity. Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma, seven neuroblastoma cell lines, and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors. (The product specifications below only indicate the effective content of Paditaxel, the actual albumin quality depends on the batch; the ratio of each ingredient in this product is Paditaxel: albumin -1:7~1:11) .
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Cat. No.: HY-FL0011
Research Areas:  

Cancer

Albumin bound-paclitaxel solution is a nanoparticle that is formed by combining Paclitaxel (HY-B0015) with human serum albumin, and it is used in research for various solid tumors such as breast cancer, lung cancer, and pancreatic cancer. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.
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Cat. No.: HY-139248
CAS No.: 2089211-45-8
Target:  

Drug Derivative

Research Areas:  

Cancer

Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively) .
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