2 Results for "

Alternative Lengthening of Telomeres (ALT)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Alternative Lengthening of Telomeres (ALT)" in MCE Product Catalog:

Cat. No.: HY-146812
CAS No.: 2675490-72-7
Target:  

G-quadruplex

Research Areas:  

Cancer

DIZ-3 is a selective multimeric G4 ligand based on a G4-ligand-dimerizing strategy. DIZ-3 intercalates into the G4-G4 interface, stabilizing the higher-order structure. DIZ-3 induces cell cycle arrest and apoptosis, and thus inhibits cell proliferation in alternative lengthening of telomere (ALT) cancer cells .
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Cat. No.: HY-P11224
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

RMI-L4 is an efficient cyclic peptide inhibitor that can specifically disrupt the interaction between FANCM and RMI proteins with an IC50 of 54 nM. RMI-L4 engages the FANCM-binding pocket of RMI1/2 with nanomolar affinity (KD = 2.5 nM). RMI-L4 cannot penetrate the cell membrane and can be used to study the FANCM-RMI pathway targeting cancer with alternate lengthening of telomeres (ALT) .
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