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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Amiodarone hydrochloride (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Amiodarone hydrochloride (Standard)" in MCE Product Catalog:
Cat. No.: HY-14188R
CAS No.: 19774-82-4
Research Areas:
Amiodarone (hydrochloride) (Standard) is the analytical standard of Amiodarone (hydrochloride). This product is intended for research and analytical applications. Amiodarone hydrochloride, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outwardIhERG tails with an IC50 of ∼45 nM . Amiodarone hydrochloride induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts . Amiodarone hydrochloride can be used in the research of both supraventricular and ventricular arrhythmias .
Cat. No.: HY-75839R
CAS No.: 141625-93-6
Research Areas:
Dronedarone (Hydrochloride) (Standard) is the analytical standard of Dronedarone (Hydrochloride). This product is intended for research and analytical applications. Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na +, K + and Ca 2+ currents.
Cat. No.: HY-A0016R
CAS No.: 141626-36-0
Synonyms: SR 33589 (Standard)
Target:
Reference Standards mAChR Sodium Channel Calcium Channel Adrenergic Receptor Cytochrome P450 Autophagy
Research Areas:
Dronedarone (Standard) is the analytical standard of Dronedarone. This product is intended for research and analytical applications. Dronedarone (SR 33589), a derivative of amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4 .
Cat. No.: HY-130353R
CAS No.: 96027-74-6
Synonyms: N-DesethylAmiodarone hydrochloride (Standard); LB 33020 hydrochloride (Standard)
Research Areas:
Desethylamiodarone hydrochloride (Standard) (N-Desethylamiodarone hydrochloride (Standard); LB 33020 hydrochloride (Standard)) is the analytical standard of Desethylamiodarone hydrochloride (HY-130353). This product is intended for research and analytical applications. Desethylamiodarone hydrochloride (N-Desethylamiodarone hydrochloride; LB 33020 hydrochloride) is the major active metabolite of Amiodarone (HY-14187) generated via CYP3A4 metabolism. Desethylamiodarone hydrochloride downregulates p‑Akt, p‑Bad and Bcl‑2, upregulates Bax, promotes mitochondrial release of cytochrome c, activates caspase‑3 and cleaves PARP‑1, thereby inducing cell cycle arrest and apoptosis. Desethylamiodarone hydrochloride can be used in cervical cancer-related research .
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Protocols
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