31 Results for "

Andrographis

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "Andrographis" in MCE Product Catalog:

34
Andrographolide
Andrographolide
0 Images
34 Publications Verification
Cat. No.: HY-N0191
CAS No.: 5508-58-7
Synonyms: Andrographis
Category:  

Infection Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

NF-κB SARS-CoV Influenza Virus Autophagy Parasite

Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
1
Neoandrographolide
Neoandrographolide
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1 Cited Publications
Cat. No.: HY-N0721
CAS No.: 27215-14-1
Synonyms: NeoAndrographiside
Category:  

Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

ERK p38 MAPK JNK NF-κB PI3K PPAR GSK-3 CaMK NO Synthase Reactive Oxygen Species (ROS) Apoptosis

Neoandrographolide is a diterpenoid compound isolated from Andrographis paniculata. Neoandrographolide inhibits osteoclasts differentiation and bone resorption through inhibition of MAPK/NF-κB/PI3K/AKT/GSK3β/PPAR/CAMK signaling pathway. Neoandrographolide inhibits apoptosis in rat embryonic ventricular cardiomyocytes. Neoandrographolide inhibits iNOS and the generation of ROS, activates eNOS, exhibiting anti-inflammatory and hypolipidemic activity .
1
Dehydroandrographolide succinate
Dehydroandrographolide succinate
0 Images
1 Cited Publications
Cat. No.: HY-N0677
CAS No.: 786593-06-4
Category:  

Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology Cancer

Target:  

Influenza Virus Prostaglandin Receptor Akt GSK-3

Dehydroandrographolide succinate can be extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used in research for viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Dehydroandrographolide succinate exerts antithrombotic effect. Dehydroandrographolide succinate significantly inhibits the platelet aggregation rate (ED50 = 386.9 mg/kg) by decreasing TXB2 levels. Dehydroandrographolide succinate mitigates muscle astrophy via the Akt/GSK3β and MuRF-1 pathways .
1
Andrograpanin
Andrograpanin
0 Images
1 Cited Publications
Cat. No.: HY-N9388
CAS No.: 82209-74-3
Category:  

Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

p38 MAPK

Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties .
1
Deoxyandrographolide
Deoxyandrographolide
0 Images
1 Cited Publications
Cat. No.: HY-N0857
CAS No.: 79233-15-1
Category:  

Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants

Target:  

GLUT HDAC Virus Protease PI3K AMPK Akt Histone Demethylase MDM-2/p53 IFNAR Reactive Oxygen Species (ROS)

Deoxyandrographolide is an orally active lactone found in the Andrographis paniculata Nees. Deoxyandrographolide shows a KD of 38.4 μM of HDAC1. Deoxyandrographolide enhances GLUT4 plasma membrane translocation, activates PI3K and AMPK-dependent signaling pathways, suppresses fasting blood glucose, serum insulin, triglycerides, and LDL-cholesterol levels. Deoxyandrographolide enhances HDAC1 expression via inhibited ubiquitination degradation, represses H3K4me3, improves chromosome stability, and restrains aging biomarkers p16, p21, γH2A.X, p53 and ROS production. Deoxyandrographolide interacts with Foot-and-Mouth Disease Virus 3Cpro active site, inhibits protease and IFN-antagonist activity, derepresses ISG expression, and inhibits viral replication. Deoxyandrographolide can be used for the researches of type 2 diabetes mellitus, vascular senescence and virus infection .
Andrographolide (Standard)
Andrographolide (Standard)
0 Images
Cat. No.: HY-N0191R
CAS No.: 5508-58-7
Synonyms: Andrographis (Standard)
Category:  

Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants

Target:  

Reference Standards NF-κB SARS-CoV Influenza Virus Autophagy Parasite

Andrographolide (Standard) is the analytical standard of Andrographolide. This product is intended for research and analytical applications. Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
Moslosooflavone
Moslosooflavone
0 Images
Cat. No.: HY-N2035
CAS No.: 3570-62-5
Category:  

Flavones Plants Medicago × varia Martyn Flavonoids Monophenols Acanthaceae Simsia foetida (Cav.) S.F.Blake Labiatae Phenols Disease Research Fields Inflammation/Immunology

Target:  

Reactive Oxygen Species (ROS)

Moslosooflavone is a flavonoid isolated from Andrographis paniculata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities .
Andrographidine G
Andrographidine G
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Cat. No.: HY-N16518
CAS No.: 1494685-00-5
Category:  

Flavonoids Monophenols Acanthaceae Simsia foetida (Cav.) S.F.Blake Flavones Phenols Plants

Target:  

Others

Andrographidine G is a new flavone glucoside. Andrographidine G can be isolated from Andrographis paniculata .
5,7,8-Trimethoxyflavone
5,7,8-Trimethoxyflavone
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Cat. No.: HY-N7656
CAS No.: 23050-38-6
Synonyms: Norwogonin 5,7,8-trimethyl ether
Category:  

Flavonoids Leguminosae Flavones Plants Disease Research Fields Lupinus micranthus Guss. Inflammation/Immunology

Target:  

NO Synthase

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity .
Andrographidine C
Andrographidine C
0 Images
Cat. No.: HY-N2866
CAS No.: 113963-39-6
Category:  

Flavonoids Acanthaceae Simsia foetida (Cav.) S.F.Blake Flavones Plants Saccharides Monosaccharides

Target:  

Others

Andrographidine C is a flavone, that can be isolated from Andrographis paniculate .
Neoandrographolide (Standard)
Neoandrographolide (Standard)
0 Images
Cat. No.: HY-N0721R
CAS No.: 27215-14-1
Synonyms: NeoAndrographiside (Standard)
Category:  

Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants

Target:  

Reference Standards ERK p38 MAPK JNK NF-κB PI3K PPAR GSK-3 NO Synthase Reactive Oxygen Species (ROS) Apoptosis

Neoandrographolide (Standard) is the analytical standard of Neoandrographolide. This product is intended for research and analytical applications. Neoandrographolide is a diterpenoid compound isolated from Andrographis paniculata. Neoandrographolide inhibits osteoclasts differentiation and bone resorption through inhibition of MAPK/NF-κB/PI3K/AKT/GSK3β/PPAR/CAMK signaling pathway. Neoandrographolide inhibits apoptosis in rat embryonic ventricular cardiomyocytes. Neoandrographolide inhibits iNOS and the generation of ROS, activates eNOS, exhibiting anti-inflammatory and hypolipidemic activity .
7-O-Methyldihydrowogonin
7-O-Methyldihydrowogonin
0 Images
Cat. No.: HY-N2676
CAS No.: 113981-49-0
Category:  

Flavonoids Flavonones Melodorum fruticosum Lour. Plants Annonaceae

Target:  

Others

7-O-Methyldihydrowogonin is a flavonoid that can be isolated from Andrographis paniculata .
Procumbide
Procumbide
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Cat. No.: HY-N1543
CAS No.: 20486-27-5
Category:  

Acanthaceae Iridoids Simsia foetida (Cav.) S.F.Blake Terpenoids Plants

Target:  

Others

Procumbide (compound 11) is a flavone glucoside. Procumbide can be isolated from Andrographis paniculata .
14-Deoxy-11-hydroxyandrographolide
14-Deoxy-11-hydroxyandrographolide
0 Images
Cat. No.: HY-N1491
CAS No.: 160242-09-1
Target:  

Others

Research Areas:  

Others

14-Deoxy-11-hydroxyandrographolide is a compound isolated from Andrographis paniculate .
14-Deoxy-17-hydroxyandrographolide
14-Deoxy-17-hydroxyandrographolide
0 Images
Cat. No.: HY-N1488
CAS No.: 869384-82-7
Synonyms: 14-Deoxy-17β-hydroxyandrographolide
Target:  

Drug Derivative

Research Areas:  

Others

14-Deoxy-17-hydroxyandrographolide is an ent-labdane diterpenoid compound isolated from the aerial parts of Andrographis paniculate .
14-Deoxy-12-hydroxyandrographolide
14-Deoxy-12-hydroxyandrographolide
0 Images
Cat. No.: HY-N1492
CAS No.: 219721-33-2
Target:  

Others

Research Areas:  

Others

14-Deoxy-12-hydroxyandrographolide is a labdane type diterpene compound isolated from the leaves of Andrographis paniculata Nees .
5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside
5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside
0 Images
Cat. No.: HY-N2663
CAS No.: 710952-13-9
Category:  

Flavonoids Acanthaceae Simsia foetida (Cav.) S.F.Blake Plants

Target:  

Others

5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside is a Flavonoids product that can be isolated from the herbs of Andrographis paniculata .
Moslosooflavone (Standard)
Moslosooflavone (Standard)
0 Images
Cat. No.: HY-N2035R
CAS No.: 3570-62-5
Category:  

Flavonoids Monophenols Acanthaceae Simsia foetida (Cav.) S.F.Blake Flavones Labiatae Phenols Plants Medicago × varia Martyn

Target:  

Reference Standards Reactive Oxygen Species (ROS)

Moslosooflavone (Standard) is the analytical standard of Moslosooflavone. This product is intended for research and analytical applications. Moslosooflavone is a flavonoid isolated from Andrographis paniculata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities .
Andrograpanin (Standard)
Andrograpanin (Standard)
0 Images
Cat. No.: HY-N9388R
CAS No.: 82209-74-3
Category:  

Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants

Target:  

Reference Standards p38 MAPK

Andrograpanin (Standard) is the analytical standard of Andrograpanin. This product is intended for research and analytical applications. Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties .
ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside
ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside
0 Images
Cat. No.: HY-N9104
CAS No.: 1245636-01-4
Category:  

Natural Products Acanthaceae Simsia foetida (Cav.) S.F.Blake Plants

Target:  

Others

ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside is a natural product derived from the leaves of Andrographis paniculata that has anti-inflammatory and antiviral activity .
Assay Types