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  5. Simsia foetida (Cav.) S.F.Blake

Simsia foetida (Cav.) S.F.Blake

Simsia foetida (Cav.) S.F.Blake (39):

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-N0191
    Andrographolide 5508-58-7 99.74%
    Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
    Andrographolide
  • HY-N0721
    Neoandrographolide 27215-14-1 99.41%
    Neoandrographolide is a diterpenoid compound isolated from Andrographis paniculata. Neoandrographolide inhibits osteoclasts differentiation and bone resorption through inhibition of MAPK/NF-κB/PI3K/AKT/GSK3β/PPAR/CAMK signaling pathway. Neoandrographolide inhibits apoptosis in rat embryonic ventricular cardiomyocytes. Neoandrographolide inhibits iNOS and the generation of ROS, activates eNOS, exhibiting anti-inflammatory and hypolipidemic activity.
    Neoandrographolide
  • HY-N9388
    Andrograpanin 82209-74-3 99.89%
    Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties.
    Andrograpanin
  • HY-N4323
    14-Deoxyandrographolide 4176-97-0 99.94%
    14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A.
    14-Deoxyandrographolide
  • HY-N1490
    14-Deoxy-11,12-didehydroandrographolide 42895-58-9 99.93%
    14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.
    14-Deoxy-11,12-didehydroandrographolide
  • HY-171664
    ent-Copalyl diphosphate 21738-30-7
    ent-Copalyl diphosphate (ent-CPP) is a terpenoid precursor and metabolite involved in plant biosynthetic pathways. ent-Copalyl diphosphate participates in metabolism of natural products including phytoalexins in rice and maize, and steviol glycoside in Stevia rebaudiana.
    ent-Copalyl diphosphate
  • HY-N19664
    14-Deoxy-12-methoxyandrographolide 142036-15-5
    14-Deoxy-12-methoxyandrographolide, an ent-labdane-type diterpenoid found in the aerial parts of Andrographis paniculata, is a cell differentiation inducer. 14-Deoxy-12-methoxyandrographolide induces differentiation of myeloid leukemia cells via increased phagocytosis of polystyrene latex particles. 14-Deoxy-12-methoxyandrographolide can be used for the research of myeloid leukemia.
    14-Deoxy-12-methoxyandrographolide
  • HY-N18352
    8-Methylandrograpanin 21681-03-8
    8-Methylandrograpanin (Compound I) is a diterpene found in the leaves of Andrographis paniculata (Burm.f.) Nees.
    8-Methylandrograpanin
  • HY-N0191R
    Andrographolide (Standard) 5508-58-7
    Andrographolide (Standard) is the analytical standard of Andrographolide. This product is intended for research and analytical applications. Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
    Andrographolide (Standard)
  • HY-N0677A
    Kalii Dehydrographolidi Succinas 76958-99-1 98.57%
    Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate) is an antibiotic. Kalii Dehydrographolidi Succinas exerts immunostimulatory, anti-infective and anti-inflammatory effects. Kalii Dehydrographolidi Succinas shows potential for research on viral pneumonia and viral upper respiratory tract infections.
    Kalii Dehydrographolidi Succinas
  • HY-N2035
    Moslosooflavone 3570-62-5 99.91%
    Moslosooflavone is a flavonoid isolated from Andrographis paniculata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities.
    Moslosooflavone
  • HY-N0677
    Dehydroandrographolide succinate 786593-06-4 99.88%
    Dehydroandrographolide succinate can be extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used in research for viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Dehydroandrographolide succinate exerts antithrombotic effect. Dehydroandrographolide succinate significantly inhibits the platelet aggregation rate (ED50 = 386.9 mg/kg) by decreasing TXB2 levels. Dehydroandrographolide succinate mitigates muscle astrophy via the Akt/GSK3β and MuRF-1 pathways.
    Dehydroandrographolide succinate
  • HY-N0857
    Deoxyandrographolide 79233-15-1 98.0%
    Deoxyandrographolide is an orally active lactone found in the Andrographis paniculata Nees. Deoxyandrographolide shows a KD of 38.4 μM of HDAC1. Deoxyandrographolide enhances GLUT4 plasma membrane translocation, activates PI3K and AMPK-dependent signaling pathways, suppresses fasting blood glucose, serum insulin, triglycerides, and LDL-cholesterol levels. Deoxyandrographolide enhances HDAC1 expression via inhibited ubiquitination degradation, represses H3K4me3, improves chromosome stability, and restrains aging biomarkers p16, p21, γH2A.X, p53 and ROS production. Deoxyandrographolide interacts with Foot-and-Mouth Disease Virus 3Cpro active site, inhibits protease and IFN-antagonist activity, derepresses ISG expression, and inhibits viral replication. Deoxyandrographolide can be used for the researches of type 2 diabetes mellitus, vascular senescence and virus infection.
    Deoxyandrographolide
  • HY-N1912
    Andropanolide 869807-57-8 98.78%
    Andropanolide is a natural product that exerts cytotoxicity toward carcinoma cells and significantly inhibits the overproduction of nitric oxide (NO) in Lipopolysaccharides (HY-D1056) (LPS)-stimulated RAW264.7 macrophages.
    Andropanolide
  • HY-N2868
    Andropanoside 82209-72-1 99.57%
    Andropanoside is a natural product and possesses a protective activity against various liver disorders.
    Andropanoside
  • HY-N13477
    Andrographidine A 113963-37-4 99.93%
    Andrographidine A is a natural product.
    Andrographidine A
  • HY-N0191A
    14-epi-Andrographolide 142037-79-4
    14-epi-andrographolide is a diterpene analog of Andrographolide (HY-N0191), which is an NF-κB inhibitor and antiviral agent.
    14-epi-Andrographolide
  • HY-N2866
    Andrographidine C 113963-39-6
    Andrographidine C is a flavone, that can be isolated from Andrographis paniculate.
    Andrographidine C
  • HY-N1543
    Procumbide 20486-27-5
    Procumbide (compound 11) is a flavone glucoside. Procumbide can be isolated from Andrographis paniculata.
    Procumbide
  • HY-N2867
    Andrographiside 82209-76-5
    Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP). Andrographiside is a novel biofilm inhibitor of Pseudomonas aeruginosa PAO1 by modulating quorum-sensing proteins.
    Andrographiside