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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
BRD9 Degrader-1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "BRD9 Degrader-1" in MCE Product Catalog:
Cat. No.: HY-156401
Target:
Research Areas:
BRD9 Degrader-1 is a selective BRD9 PROTAC degrader with a DC50 of 108 nM. BRD9 Degrader-1 induces the formation of a ternary complex between BRD9 and VHL, with an EC50 of 17 nM, and shows no hook effect at high concentrations. BRD9 Degrader-1 can be used for the research of synovial sarcoma [1].
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3 Cited Publications
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PROTAC BRD9 Degrader-1 is a PROTAC connected by ligands for Cereblon and BRD9 (IC50=13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology [1].
Cat. No.: HY-168695
Research Areas:
BRD9 ligand-7 is a Ligand for Target Protein for PROTAC. CSI118 TFA can be used to synthesize BRD9 Degrader-1 (HY-156401) [1].
Cat. No.: HY-168694
Research Areas:
E3 Ligase Ligand-linker Conjugate 147 is a conjugate of E3 ligase ligand and PROTAC Linker, which can be used to synthesize BRD9 Degrader-1 (HY-156401) (Compound 13-7) [1]. E3 Ligase Ligand-linker Conjugate 147 is composed of the E3 ligase ligand BRD9 ligand-7 (HY-168695) and the PROTA linker 2-((1R,5S,6s)-3-Azabicyclo[3.1.0]hexan-6-yl)ethan-1-ol (HY-W763939).
Cat. No.: HY-W763939
CAS No.: 1354427-47-6
Target:
Research Areas:
2-[(1R,5S,6R)-3-Azabicyclo[3.1.0]hexan-6-yl]ethan-1-ol is a PROTAC linker that can be used for the synthesis of PROTACs, such as BRD9 Degrader-1 (HY-156401) [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
