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Biotin-PEG4-Dde-TAMRA-PEG3-Azide

" in MedChemExpress (MCE) Product Catalog:

46

Inhibitors & Agonists

48

Peptides

4

Click Chemistry

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-P11307

    Proteasome Cancer
    Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma .
    Biotin-epoxomicin
  • HY-P10303

    Cyclo[RGDfK(Azide)]

    Biochemical Assay Reagents Others
    Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is the derivative of Cyclo(-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
    Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)]
  • HY-P11306

    Proteasome NF-κB Inflammation/Immunology
    Biotin-(Oaa)3-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)3-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain .
    Biotin-(Oaa)3-epoxomicin
  • HY-141091

    Fluorescent Dye Others
    Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Biotin-PEG4-Dde-TAMRA-PEG3-Azide
  • HY-P10620

    Bacterial Others
    GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .
    GGGYK-Biotin
  • HY-P3576A

    Fluorescent Dye Bombesin Receptor Neurological Disease Cancer
    Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .
    Biotin-Gastrin Releasing Peptide, human TFA
  • HY-P2546

    Neurokinin Receptor Neurological Disease
    Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
    Biotin-Substance P
  • HY-P5112A

    Azido-PEG3-FLAG TFA

    Biochemical Assay Reagents Others
    Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    Azido-PEG3-DYKDDDDK TFA
  • HY-P10398

    ADAMTS Others
    5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA is a substrate for ADAMTS-4/ADAMTS-5, and can be used to detect ADAMTS-4 or ADAMTS-5 activity .
    5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA
  • HY-P3432

    Biochemical Assay Reagents Others
    DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
    DfTat
  • HY-P10886

    Gap Junction Protein Claudin Inflammation/Immunology
    Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .
    Zifogaptide
  • HY-P5351A

    Transmembrane Glycoprotein Inflammation/Immunology Cancer
    Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .
    Hyaluronan-binding peptide, biotin labeled TFA
  • HY-P2491

    Fluorescent Dye Cardiovascular Disease Endocrinology
    Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
    Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled
  • HY-P2136F

    Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .
    Biotin-COG1410 TFA
  • HY-P11118A

    CAPture peptide, Biotin-CCDC61 (334-366) TFA

    Biochemical Assay Reagents Others
    Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .
    Biotinylated CCDC61 peptide TFA
  • HY-P4083

    Fluorescent Dye Others
    (Arg)9,TAMRA-labeled is a TAMRA-labeled cell permeable peptide. (Arg)9 is a cell-permeable peptide used for drug delivery .
    (Arg)9,TAMRA-labeled
  • HY-P5112

    Azido-PEG3-FLAG

    Biochemical Assay Reagents Others
    Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    Azido-PEG3-DYKDDDDK
  • HY-169089

    Drug Derivative Cancer
    RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .
    RP-182-PEG3-K(palmitic acid)-NH2
  • HY-P3844

    Transmembrane Glycoprotein Neuropeptide B/W Receptor Neurological Disease
    Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8) .
    Biotinyl-neuropeptide W-23 (human)
  • HY-P2549

    Fluorescent Dye Neurological Disease
    Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.
    Biotin-β-Amyloid (1-40)
  • HY-P11026

    DOTA-PEG4-TMVP1446

    VEGFR Cancer
    DOTA-TMVP1446 is a VEGFR-3 targeting peptide. DOTA-TMVP1446 labeled with 68Ga accurately detectes the status of lymph node metastasis, even in micrometastatic tumors, in the B16-F10 tumor mice model. DOTA-TMVP1446 can be used as a radiotracer for cancer-metastatic sentinel lymph nodes (m-SLN) imaging .
    DOTA-TMVP1446
  • HY-P11270

    BGM0504; BG128

    Insulin Receptor GLP Receptor Metabolic Disease
    Relsipatide (BG128) is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
    Relsipatide
  • HY-P2510

    Thyroid Hormone Receptor Metabolic Disease
    Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
    Parathyroid Hormone (1-34), human, biotinylated
  • HY-P4105

    Amino Acid Derivatives Others
    TAT (47-57), TAMRA-labeled is a TAMRA-labeled peptide with cell-penetrating activity.
    TAT (47-57), TAMRA-labeled
  • HY-P10569

    EGFR Cancer
    Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a Km value of 60 μm for Her2/neu kinase domain .
    Biotin HER-2 substrate peptide
  • HY-13443F

    Lys27(Biotin)-Exendin 4

    GCGR Others
    Exendin 4, biotin labeled is a biotin labeled Exendin 4 (HY-13443). Exendin 4 is a long-acting GLP-1 receptor agonist .
    Exendin 4, biotin labeled
  • HY-169089A

    Drug Derivative Cancer
    RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .
    RP-182-PEG3-K(palmitic acid)-NH2 TFA
  • HY-P10590

    Fluorescent Dye Cancer
    Talogreptide mesaroxetan is a diagnostic imaging agent, with antineoplastic effect .
    Talogreptide mesaroxetan
  • HY-P10319

    PKA Cardiovascular Disease Cancer
    RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .
    RI-STAD-2
  • HY-P2551

    Amyloid-β Neurological Disease
    Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-β(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP) .
    Biotin-β-Amyloid (17-40)
  • HY-P11118

    CAPture peptide, Biotin-CCDC61 (334-366)

    Biochemical Assay Reagents Others
    Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide specifically isolates intact centrosomes .
    Biotinylated CCDC61 peptide
  • HY-P2504

    Syk Others
    Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
    Syk Kinase Peptide Substrate, Biotin labeled
  • HY-P3576

    Fluorescent Dye Bombesin Receptor Neurological Disease Cancer
    Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .
    Biotin-Gastrin Releasing Peptide, human
  • HY-P0030

    Fluorescent Dye Others
    5-Tamra-DRVYIHP i a Peptide with TAMRA labeling oligonucleotide.
    5-Tamra-DRVYIHP
  • HY-P10906

    Biochemical Assay Reagents Others
    Talovirtide is a peptide containing L-valyl .
    Talovirtide
  • HY-P11455

    Liposome Others
    Lipopeptide CPE4 is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research .
    Lipopeptide CPE4
  • HY-P10872

    SARS-CoV Infection
    P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC50s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC50 of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models .
    P315V3
  • HY-P10566

    BCL6 Cancer
    BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an KD value of 1.32 µM. BCOR(498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells .
    BCOR(498-514), biotinylated
  • HY-P10372

    Src Cancer
    pFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) .
    pFYN peptide
  • HY-P10468

    ADAMTS Others
    5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 is a substrate for ADAMTS-4/ADAMTS-5, and can be used to detect ADAMTS-4 or ADAMTS-5 activity .
    5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2
  • HY-P4083A

    Fluorescent Dye Others
    (Arg)9,TAMRA-labeled acetate is a TAMRA-labeled, membrane-permeable cationic cell-penetrating polyarginine peptide. (Arg)9,TAMRA-labeled acetate acts as a cell-penetrating peptide for drug delivery .
    (Arg)9,TAMRA-labeled acetate
  • HY-P11461

    Biotin-corticotropin releasing factor

    Drug Derivative Neurological Disease
    Biotin-CRF, human, rat is a biotin-conjugated CRF (human, rat). CRF (human, rat) is a corticotropin-releasing hormone, paraventricular hypothalamic nucleus marker .
    Biotin-CRF, human, rat
  • HY-P11773

    Radionuclide-Drug Conjugates (RDCs) Integrin Others
    3P-RGD2 is a dimeric cyclic RGD (Arg-Gly-Asp) peptide. When radiolabeled with 99mTc, 3P-RGD2 serves as a selective radiotracer for integrin αvβ3. When radiolabeled with 99mTc, 3P-RGD2 enables single-photon emission computed tomography imaging of integrin αvβ3 .
    3P-RGD2
  • HY-P11774

    Integrin Cancer
    HYNIC-3P-RGD2 is a dimeric cyclic RGD peptide with high binding affinity for integrin αvβ3 (IC50 = 33 nM). HYNIC-3P-RGD2 acts as a precursor molecule for radiotracers and is used to detect tumor angiogenesis .
    HYNIC-3P-RGD2
  • HY-P11488

    Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA Cancer
    JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
    JR11-PEG3-DOTA-PSMA-03
  • HY-P11485

    Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA Cancer
    JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
    JR11-PEG3-HBED-CC-PSMA-03

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