64 Results for "

CD19 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (64)

64 Results for "CD19 Antibody" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-15579
CAS No.: 745017-94-1
Purity:  99.92%
Synonyms: Monomethylauristatin F
Research Areas:  

Cancer

MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A .
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8
8 Publications Verification
Cat. No.: HY-15579A
CAS No.: 1415246-68-2
Purity:  99.93%
Synonyms: Monomethylauristatin F hydrochloride
Research Areas:  

Cancer

MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A .
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8
8 Publications Verification
Cat. No.: HY-15579B
CAS No.: 1799706-65-2
Purity:  99.59%
Synonyms: Monomethylauristatin F sodium
Research Areas:  

Cancer

MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A .
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3
3 Cited Publications
Cat. No.: HY-P9963
CAS No.: 853426-35-4
Synonyms: bscCD19xCD3; AMG-103; MEDI-538; MT-103; BLINCYTO

Target:  

CD19

Research Areas:  

Cancer

Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia .
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2
2 Cited Publications
Cat. No.: HY-P9981
CAS No.: 1422527-84-1
Synonyms: XmAb5574; MOR00208; Tafasitamab-cxix; MOR-208

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Tafasitamab (XmAb5574) is an Fc-modified, humanized monoclonal antibody that binds to the human B-cell surface antigenCD19 .
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2
2 Cited Publications
Cat. No.: HY-P99711
CAS No.: 1875032-68-0
Synonyms: RB4v1.2

Target:  

CD19 ADC Antibodies

Research Areas:  

Cancer

Loncastuximab (RB4v1.2) is an anti-CD19 monoclonal antibody. Loncastuximab has antitumor activity and can be used in the research of Non-Hodgkin Lymphoma (NHL) and Diffuse Large B-cell Lymphoma (DLBCL). Loncastuximab is capable of synthesizing the ADC molecule Loncastuximab tesirine (HY-P99349) .
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1
1 Cited Publications
Cat. No.: HY-P99113
CAS No.: 1299440-37-1
Synonyms: MEDI-551
Inebilizumab is an anti-CD19 monoclonal antibody (mAb) with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used for multiple sclerosis and neuromyelitis optica research .
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1
1 Cited Publications
Cat. No.: HY-P99285
CAS No.: 1630074-14-4
Synonyms: hBU 12

Target:  

ADC Antibodies CD19

Research Areas:  

Cancer

Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab binds to CD19 on the surface of B cells. Denintuzumab can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia .
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1
1 Cited Publications
Cat. No.: HY-P990571

Target:  

CD19

Research Areas:  

Inflammation/Immunology

Coltuximab is a CHO-expressed humanized antibody that targets CD19. Coltuximab is composed of huIgG1 heavy chains and huκ light chains, with a molecular weight (MW) of 144.70 kDa. The isotype control for Coltuximab can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P99349
CAS No.: 1879918-31-6
Synonyms: Loncastuximab tesirine-lpyl; ADCT-402

Research Areas:  

Cancer

Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). The antibody portion is Loncastuximab (HY-P99711), and the drug-linker conjugate for ADC is Tesirine (HY-128952). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma .
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Cat. No.: HY-P991028
CAS No.: 2892667-02-4
Synonyms: AZD0486; TNB-486

Research Areas:  

Cancer

Surovatamig (AZD0486; TNB-486) is a fully human anti-CD19/CD3 IgG4 bispecific antibody. Surovatamig triggers T cell activation, releases cytotoxic granules, and induces T cell-dependent cellular cytotoxicity and tumor cell lysis. Surovatamig can reduces release of pro-inflammatory cytokines including IL-2, IFNγ, TNF. Surovatamig can be used for the research of cancer, such as B cell non-Hodgkin lymphoma .
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Cat. No.: HY-P99868
CAS No.: 1831098-91-9
Synonyms: MGD 011

Target:  

CD19 CD3

Research Areas:  

Cancer

Duvortuxizumab (MGD 011) is a chimeric humanized IG antibody targeting CD19 and CD3E .
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Cat. No.: HY-P99113A

Target:  

CD19

Inebilizumab (FUT8-KO) is an anti-CD19 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.Inebilizumab (FUT8-KO) exhibits enhanced ADCC against B cells and can be used for research on multiple sclerosis and neuromyelitis optica .
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Cat. No.: HY-P99761
CAS No.: 1690307-05-1
Synonyms: XmAb5871

Target:  

CD19 Apoptosis

Research Areas:  

Inflammation/Immunology

Obexelimab (XmAb5871) is a humanized anti-CD19 antibody. Obexelimab works by inhibiting B cell receptor (BCR) mediated calcium influx and promoting the phosphorylation of Fc γ receptor IIb (FcγRIIb), which reduces B cell activation and function, leading to B cell apoptosis. Obexelimab can be used in research for rheumatoid arthritis and systemic lupus erythematosus .
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Cat. No.: HY-P99976

Target:  

CD19

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD19 Antibody (1D3) is an IgG2a antibody inhibitor targeting mouse CD19. Anti-Mouse CD19 Antibody (1D3) reduces CD19 expression levels on the surface of B cells. Anti-Mouse CD19 Antibody (1D3) inhibits the replication of peritoneal B-1a cells .
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Cat. No.: HY-P990017
CAS No.: 2417199-08-5
Synonyms: CD19-4-1BBL; RO7227166; RG6076

Target:  

CD19

Research Areas:  

Cancer

Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human 41BBL. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells .
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Cat. No.: HY-P990870

Research Areas:  

Inflammation/Immunology

Anti-CD19 Antibody (4G7) is an anti-human CD19 IgG1 monoclonal antibody. Anti-CD19 Antibody (4G7) reduces the killing effect of CAR T cells on Raji cells. Anti-CD19 Antibody (4G7) can be used for research on immunology. Anti-CD19 Antibody (4G7) is often used in flow cytometry. The recommend isotype control of Anti-CD19 Antibody (4G7): Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-P99914
CAS No.: 2559704-23-1
Synonyms: GNC-038
Emfizatamab (GNC-038) is a monoclonal antibody against CD19/CD3E/TNFRSF9/PD-L1. Emfizatamab exhibits antitumor activity, being capable of activating CD3 and 4-1BB signals on T cells, as well as targeting the high expression of CD19 or PD-L1 on tumor cells. Emfizatamab functions as a CD19-specific T cell engager by mediating direct antitumor activity. Emfizatamab can also overcome the inhibition of T cells by PD-L1. Emfizatamab can be used in the research of tumors such as R/R non-Hodgkin lymphoma or acute lymphoblastic leukemia .
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Cat. No.: HY-P990349

Target:  

CD19

Research Areas:  

Inflammation/Immunology

The Anti-CD19 Antibody is a humanized antibody expressed in CHO cells, targeting CD19. The Anti-CD19 Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-CD19 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990729
CAS No.: 2720478-38-4
Synonyms: VB-119

Target:  

CD19

Research Areas:  

Inflammation/Immunology

Budoprutug is an anti-CD19 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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