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Denintuzumab

(Synonyms: hBU 12)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab binds to CD19 on the surface of B cells. Denintuzumab can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia.

For research use only. We do not sell to patients.

  • Purity: ≥99.0%
  • CAS No.: 1630074-14-4
  • Molecular Weight:145.96 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Denintuzumab
  • Experimental Validation Results for Denintuzumab
  • Experimental Validation Results for Denintuzumab
  • Denintuzumab Chemical Structure
    Denintuzumab Chemical Structure
CAS No.: 1630074-14-4
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609-228-6898
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CD19 (red) with Denintuzumab (anti-CD19) (HY-P99285). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • 1/16

    Immobilized Hu-CD19-VLP can bind Denintuzumab. The EC50 for this effect is 16 ng/mL.

  • Denintuzumab Chemical Structure
    1/16
  • Denintuzumab
  • Flow Cytometry analysis of Raji cells labelling CD19 (red) with Denintuzumab (anti-CD19) (HY-P99285). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.
  • Immobilized Hu-CD19-VLP can bind Denintuzumab. The EC50 for this effect is 16 ng/mL.
  • IgG1-kappa