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Inebilizumab (FUT8-KO)

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Based on 1 Customer Validation

Inebilizumab (FUT8-KO) is an anti-CD19 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.Inebilizumab (FUT8-KO) exhibits enhanced ADCC against B cells and can be used for research on multiple sclerosis and neuromyelitis optica.

For research use only. We do not sell to patients.

  • Purity: 99.84%
  • Molecular Weight:146.3 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Inebilizumab (FUT8-KO)
  • Experimental Validation Results for Inebilizumab (FUT8-KO)
  • Experimental Validation Results for Inebilizumab (FUT8-KO)
  • Inebilizumab (FUT8-KO) Chemical Structure
    Inebilizumab (FUT8-KO) Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Other Forms of Inebilizumab (FUT8-KO):

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Loaded Inebilizumab (FUT8-KO) on ProA biosensor, can bind CD19 Protein, Human (HEK293, His, HY-P74330) with an affinity constant of 2.984E-09 M as determined in BLI assay.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CD19 (red) with Inebilizumab (FUT8-KO) (HY-P99113A). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Inebilizumab (FUT8-KO) Chemical Structure
    1/16
  • Inebilizumab (FUT8-KO)
  • Loaded Inebilizumab (FUT8-KO) on ProA biosensor, can bind CD19 Protein, Human (HEK293, His, HY-P74330) with an affinity constant of 2.984E-09 M as determined in BLI assay.
  • Flow Cytometry analysis of Raji cells labelling CD19 (red) with Inebilizumab (FUT8-KO) (HY-P99113A). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa