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Duvortuxizumab

(Synonyms: MGD 011)
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Based on 1 Customer Validation

Duvortuxizumab (MGD 011) is a chimeric humanized IG antibody targeting CD19 and CD3E.

For research use only. We do not sell to patients.

  • Purity: ≥99.0%
  • CAS No.: 1831098-91-9
  • Molecular Weight:109.139 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Duvortuxizumab
  • Experimental Validation Results for Duvortuxizumab
  • Experimental Validation Results for Duvortuxizumab
  • Experimental Validation Results for Duvortuxizumab
  • Duvortuxizumab Chemical Structure
  • Experimental Validation Results for Duvortuxizumab
  • Experimental Validation Results for Duvortuxizumab
  • Experimental Validation Results for Duvortuxizumab
  • Experimental Validation Results for Duvortuxizumab
  • Duvortuxizumab Chemical Structure
    Duvortuxizumab Chemical Structure
CAS No.: 1831098-91-9
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    scFv-h-CH2-CH3(_scFv)_h-CH2-CH3

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Duvortuxizumab (HY-P99868). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • 1/16

    Loaded Duvortuxizumab on AHC2 biosensor, can bind CD19 Protein, Human (HEK293, His, HY-P74330) with an affinity constant of <1.000E-11 M as determined in BLI assay.

  • 1/16

    Loaded Duvortuxizumab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 7.349E-10 M as determined in BLI assay.

  • Duvortuxizumab Chemical Structure
    1/16
  • Duvortuxizumab
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Duvortuxizumab (HY-P99868). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • Loaded Duvortuxizumab on AHC2 biosensor, can bind CD19 Protein, Human (HEK293, His, HY-P74330) with an affinity constant of <1.000E-11 M as determined in BLI assay.
  • Loaded Duvortuxizumab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 7.349E-10 M as determined in BLI assay.
  • scFv-h-CH2-CH3(_scFv)_h-CH2-CH3