19 Results for "

CD20 protein

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "CD20 protein" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-P99731
CAS No.: 899796-83-9
Synonyms: hLL1; MEDI-115

Target:  

CD74

Research Areas:  

Cancer

Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death .
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Cat. No.: HY-P990954
CAS No.: 2850355-94-9
Synonyms: IMM-0306

Target:  

CD47 CD20

Research Areas:  

Cancer

Amulirafusp alfa (IMM-0306) is a fusion protein of CD20 monoclonal antibody (mAb) with the CD47 binding domain of SIRPα, with human CD20 Kd 2.45 nM and human CD47 Kd 4.91 nM. Amulirafusp alfa binds to CD20 and CD47 on B cells, engages FcɣR, blocks CD47-SIRPα interaction, activates macrophages, NK cells, and complement cascade, mediates phagocytosis and cytotoxicity, inhibits apoptosis of Jurkat-CSR cells, reverses IL-16 tumor-promoting effects, and binds human/cynomolgus CD47 but not mouse/rat CD47. Amulirafusp alfa can be used for the research of hematological malignancies, relapsed or refractory CD20-positive B-cell non-Hodgkin’s lymphoma, relapsed or refractory B-cell non-Hodgkin lymphoma, and activated B-cell-like diffuse large B-cell lymphoma .
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Cat. No.: HY-P992417

Target:  

CD20 Apoptosis

Research Areas:  

Cancer

MT-3724 is a CD20-targeted endotoxin B. MT-3724 binds to CD20, triggers receptor internalization, traffics to the endoplasmic reticulum, and induces permanent ribosomal inactivation to mediate cell killing. MT-3724 can inhibit protein synthesis and promote tumor cell apoptosis. MT-3724 can be used for the research of relapsed or refractory B-cell non-Hodgkin’s lymphomas and diffuse large B-cell lymphoma .
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Cat. No.: HY-P7896
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P71758
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Mouse
Source:  
P. pastoris
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Cat. No.: HY-P78543
Purity:  ≥ 95%, as determined by HPLC.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7896A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P78086
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P700898
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704446
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P75433
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704449
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78579
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P700444
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Dog
Source:  
HEK293
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Cat. No.: HY-P704448
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Dog
Source:  
HEK293
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Cat. No.: HY-P704451
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704988
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte An
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-L177
1,939 compounds

Antibody inhibitors are compounds with the same activity as the original therapeutic antibodies, which can be used as positive controls for drug efficacy evaluation and other studies. Antibody inhibitors can also assist in verifying the functional activity of the target protein. These antibody inhibitors are active in vivo and can achieve certain physiological functions by blocking or neutralizing target proteins, such as CD20, HER2, EGFR, VEGFR, TNF-α, etc. In drug screening, antibody inhibitor-based screening can be carried out to identify active compounds targeting target proteins and target diseases.

MCE can provide 1,939 antibody inhibitors that can be used for drug development in cancer, immunity, infection and other hot research areas.

Cat. No.: HY-P85905
Synonyms: CD20; CK 20; CK-20; CK20; CytokeRatin-20; CytokeRatin20; K1C20_HUMAN; K20; KA20; KeRatin 20; keRatin 20, type I; keRatin 21, Rat, homolog of; KeRatin; KeRatin type I cytoskeletal 20; KeRatin-20; KeRatin20; KRT 20; KRT 21; KRT20; KRT21; MGC35423; OTTHUMP00000164518; protein IT; type I cytoskeletal 20

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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