1 Result for "

CYP1A1 variant

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CYP1A1 variant" in MCE Product Catalog:

Cat. No.: HY-113040A
CAS No.: 725246-18-4
Purity:  ≥93.0%
Synonyms: 17(R),18(S)-EETeTr
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

(17R,18S)-Epoxyeicosatetraenoic acid (17 (R),18 (S)-EETeTr) is a physiologically active fatty acid metabolite and also a vasodilator targeting BKα. (17R,18S)-Epoxyeicosatetraenoic acid activates the outward potassium current mediated by BK channels, and this effect is independent of the BKβ1 subunit, intracellular/extracellular calcium levels, and sarcoplasmic reticulum calcium release regulated by RyR3. (17R,18S)-Epoxyeicosatetraenoic acid is produced by the epoxidation of eicosapentaenoic acid mediated by CYP1A1 variants. (17R,18S)-Epoxyeicosatetraenoic acid is applicable to research related to arrhythmia .
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