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Results for "

Canine Thrombin

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Peptides

Targets Recommended:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-P1636
    Hirudin (54-65)

    		Thrombin YAP Calcium Channel Metabolic Disease
    Hirudin (54-65) is a thrombin antagonist and YAP suppressor with anticoagulatory properties.Hirudin (54-65) blocks thrombin's anion binding site, acts on soluble and thrombus-bound thrombin.Hirudin (54-65) suppresses thrombin-induced profibrotic YAP activity, reduces YAP expression, nuclear translocation, and downstream effector signaling in vascular endothelial cells.Hirudin (54-65) ameliorates obstructive cholestasis, attenuates liver fibrosis symptoms, fibrosis-associated angiogenesis, and endothelial-to-mesenchymal transition.Hirudin (54-65) reduces liver inflammation and tissue hypoxia.Hirudin (54-65) promotes extracellular calcium influx through L-type calcium channels in canine coronary artery smooth muscle, mediates contraction.Hirudin (54-65) induces endothelium-independent contraction of canine coronary arterial segments; this response is not affected by indomethacin pretreatment.Hirudin (54-65) can be used for the research of liver obstructive cholestasis, liver fibrosis .
    Hirudin (54-65)
  • HY-E70544B
    Canine Factor X

    		Biochemical Assay Reagents Cardiovascular Disease
    Canine Factor X is prepared from freshly collected canine plasma and, after activation, can convert prothrombin to thrombin .
    Canine Factor X
  • HY-114164F
    Canine Thrombin

    		Thrombin Protease Activated Receptor (PAR) MMP VEGFR Epigenetic Reader Domain Cardiovascular Disease
    Canine Thrombin is a Canine serine protease that plays a central role in blood coagulation. Canine Thrombin stimulates macrophages to polarize into a unique phenotype characterized by anti-inflammatory and pro-repair properties. Canine Thrombin activates PAR1, induces the production of MCP-1, MMP3 and VEGF in intervertebral discs, and causes degradation of the cartilage matrix and destruction of intervertebral disc structure. Canine Thrombin activity increases significantly in paraoxon-induced status epilepticus .
    Canine Thrombin
  • HY-E70544A
    Bovine Factor X

    		Factor Xa Cardiovascular Disease
    Bovine Factor X is a bovine derived coagulation factor. Canine Factor X can be converted to activated Factor Xa, which can can convert prothrombin to thrombin .
    Bovine Factor X
  • HY-E70544C
    Rabbit Factor X

    		Biochemical Assay Reagents Cardiovascular Disease
    Rabbit Factor X is a rabbit derived coagulation factor. Canine Factor X can be converted to activated Factor Xa, which can can convert prothrombin to thrombin .
    Rabbit Factor X

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