2 Results for "

Carvedilol Glucuronide

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Carvedilol Glucuronide" in MCE Product Catalog:

Cat. No.: HY-137387
CAS No.: 114869-83-9
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease Others

Carvedilol Glucuronide is the metabolite of Carvedilol (HY-B0006). Carvedilol (BM 14190) is an antagonist for β/α-1 adrenergic receptor. Carvedilol inhibits lipid peroxidation with an IC50 of 5 μM. Carvedilol is an antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome .
loading...
    loading...
Cat. No.: HY-E72116
Target:  

UGT

Human UGT2B4 is a UDP-glucuronosyltransferase. UGT2B4 catalyzes the glucuronidation of bile acids, Carvedilol (HY-B0006) and 6-hydroxylated bile acids to form glucuronide derivatives. UGT2B4 participates in the inactivation of endogenous and exogenous substances, including catechol estrogens, C19 steroids, phenols and monoterpenoids. Human UGT2B4 can be used in the research of hypertension, angina pectoris, chronic heart failure and intrahepatic cholestasis .
loading...
    loading...