2 Results for "

Cerebrotendinous xanthomatosis

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Cerebrotendinous xanthomatosis" in MCE Product Catalog:

Cat. No.: HY-171949
CAS No.: 18866-87-0
Synonyms: 3α,7α,12α,25-Tetrahydroxycoprostane
5β-Cholestane-3α,7α,12α,25-tetrol (3α,7α,12α,25-Tetrahydroxycoprostane) is a bile acid alcohol. 5β-Cholestane-3α,7α,12α,25-tetrol is a GPBAR1 (also known as TGR5) activator (EC50: 1.36 μM). 5β-Cholestane-3α,7α,12α,25-tetrol is the predominant bile-alcohol disease marker present in patients with Cerebrotendinous xanthomatosis (CTX) .
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Cat. No.: HY-186296
CAS No.: 59000-66-7
Target:  

Acyltransferase

Research Areas:  

Metabolic Disease

Cholestanol stearate serves as a substrate for plasma lecithin:cholesterol acyltransferase (LCAT), with an esterification rate of approximately 70% that of cholesterol. Cholestanol stearate contains both hydrophilic and lipophilic groups, and its components are related to the structural substances of natural products. Cholestanol stearate can be used in studies related to cerebrotendinous xanthomatosis and familial lecithin:cholesterol acyltransferase deficiency .
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