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Chemical crosslinker

" in MedChemExpress (MCE) Product Catalog:

23

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16

Biochemical Assay Reagents

2

Click Chemistry

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0623
    N-Hydroxysuccinimide
    5+ Cited Publications

    HOSu; 1-Hydroxy-2,5-pyrrolidinedione

    Biochemical Assay Reagents Others
    N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .
    N-Hydroxysuccinimide
  • HY-111434A

    UAA crosslinker 1 hydrochloride

    Amino Acid Derivatives Cancer
    N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride (UAA crosslinker 1 hydrochloride) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research .
    N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride
  • HY-W041994

    Fructose-1,6-bisphosphate aldolase Biochemical Assay Reagents Cancer
    GMBS is a heterobifunctional crosslinker targeting primary amines and sulfhydryl groups. GMBS can be used for chemical crosslinking of proteins and crosslinking mass spectrometry (CXMS) to study protein folding and map interfaces between interacting proteins .
    GMBS
  • HY-150014

    Others Others
    AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
    AMT-NHS
  • HY-107783

    Biochemical Assay Reagents Others
    Sulfo-GMBS is a crosslinker widely used in chemical modification and coupling reactions of proteins and peptides. Among amine-thiol crosslinkers, Sulfo-GMBS generates the largest number of crosslinks and covers most of the crosslinks identified by AMAS and GMBS .
    Sulfo-GMBS
  • HY-111434

    UAA crosslinker 1

    Amino Acid Derivatives Cancer
    N6-[(2-Azidoethoxy) carbonyl]-L-lysine (UAA crosslinker 1) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy) carbonyl]-L-lysine mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy) carbonyl]-L-lysine is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research .
    N6-[(2-Azidoethoxy)carbonyl]-L-lysine
  • HY-W017588

    Biochemical Assay Reagents Others
    N-(2-Hydroxyethyl)maleimide is a cross-linker. N-(2-Hydroxyethyl)maleimide is used for chemical synthesis .
    N-(2-Hydroxyethyl)maleimide
  • HY-117080

    Biochemical Assay Reagents Others
    Sulfo-EGS is a homobifunctional, amine-reactive chemical crosslinker. Sulfo-EGS is used to study protein-protein or protein-peptide interactions, which can determine the spatial proximity of amino acid residues in a protein complex, without relying on standards .
    Sulfo-EGS
  • HY-177767

    Biochemical Assay Reagents Others
    EY-CBS is a synthetic and rigid cross linker. EY-CBS reacts selectively with cysteines in a-helices, to stabilize the connecting helix. EY-CBS can be used for the study of the structural stability of protein polypeptides .
    EY-CBS
  • HY-W1048572D

    Azide-PEG3400-Amine

    PROTAC Linkers Others
    N3-PEG3400-NH2 (Azide-PEG3400-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG3400-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG3400-NH2
  • HY-W1048572C

    Azide-PEG1000-Amine

    Biochemical Assay Reagents Others
    N3-PEG1000-NH2 (Azide-PEG1000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG1000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG1000-NH2
  • HY-W1049071D

    Biochemical Assay Reagents Others
    HO-PEG40000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG40000-SCM
  • HY-W1048572A

    PROTAC Linkers Others
    N3-PEG2000-NH2 is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG2000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG2000-NH2
  • HY-W1048572H

    Azide-PEG10000-Amine

    PROTAC Linkers Others
    N3-PEG10000-NH2 (Azide-PEG10000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG10000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG10000-NH2
  • HY-W1048572I

    Azide-PEG20000-Amine

    PROTAC Linkers Others
    N3-PEG20000-NH2 (Azide-PEG20000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG20000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG20000-NH2
  • HY-W1049071H

    Biochemical Assay Reagents Others
    HO-PEG2000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG2000-SCM
  • HY-W1049071C

    Biochemical Assay Reagents Others
    HO-PEG20000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG20000-SCM
  • HY-W1049071A

    Biochemical Assay Reagents Others
    HO-PEG5000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG5000-SCM
  • HY-W1049071I

    Biochemical Assay Reagents Others
    HO-PEG3400-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG3400-SCM
  • HY-W1049071B

    Biochemical Assay Reagents Others
    HO-PEG10000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG10000-SCM
  • HY-W1049071E

    Biochemical Assay Reagents Others
    HO-PEG1000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG1000-SCM
  • HY-W1048572E

    PROTAC Linkers Others
    N3-PEG5000-NH2 is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG5000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG5000-NH2
  • HY-W1048572J

    Azide-PEG40000-Amine

    PROTAC Linkers Others
    N3-PEG40000-NH2 (Azide-PEG40000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG40000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG40000-NH2

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