1994331-17-7
![N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-111434a.gif "N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride Chemical Structure")
Chemical Structure
N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride
Synonym(s): UAA crosslinker 1 hydrochloride
- CAS No.: 1994331-17-7
- Formula:C9H18ClN5O4
- Molecular Weight:295.72
IUPAC Name: N6-((2-azidoethoxy)carbonyl)-L-lysine hydrochloride
InChIKey: USQKPJVGUFZIJQ-FJXQXJEOSA-N
SMILES: N[C@@H](CCCCNC(OCCN=[N+]=[N-])=O)C(O)=O.[H]Cl
Biological Activity: N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride (UAA crosslinker 1 hydrochloride) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research[1].
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N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride | 98.0% | N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride (UAA crosslinker 1 hydrochloride) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research. | ||||||||||||||||||||
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N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride (Standard) | ≥98% | UAA crosslinker 1 hydrochloride (Standard) is the analytical standard of UAA crosslinker 1 (hydrochloride) (HY-111434A). This product is intended for research and analytical applications. UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by maKing use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases. UAA crosslinker 1 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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