3 Results for "

Chikusetsusaponin Iva

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Chikusetsusaponin Iva" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0818
CAS No.: 51415-02-2
Synonyms: Calenduloside F
Chikusetsusaponin IVa is an orally active protein kinase activator. Chikusetsusaponin IVa binds to YAP with a KD value of 0.388 mM. Chikusetsusaponin IVa reduces inflammatory mediators (IL-6, IL-10, COX-2) expression, NO production, promotes ROS generation, induces Apoptosis, inhibits MAPK, TAZ, and regulates Nrf2, JAK/STAT. Chikusetsusaponin Iva has anti-H9N2 AIV and anti-endometrial cancer activities. Chikusetsusaponin Iva shows anti-inflammatory, hepatoprotective and osteoprotective effects .
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Cat. No.: HY-N0818R
CAS No.: 51415-02-2
Synonyms: Calenduloside F (Standard)
Chikusetsusaponin Iva (Standard) is the analytical standard of Chikusetsusaponin Iva. This product is intended for research and analytical applications.
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Cat. No.: HY-N17736
CAS No.: 58546-61-5
Synonyms: CME
Chikusetsusaponin IVa methyl ester (CME) is a natural triterpenoid saponin compound. Chikusetsusaponin IVa methyl ester induces G0/G1 cell cycle arrest and apoptosis in colon cancer cells by inhibiting the Wnt/β-catenin signaling pathway. By inhibiting the NF-κB and AP-1 signaling pathways, Chikusetsusaponin IVa methyl ester significantly reduces the production of NO, PGE₂ and pro-inflammatory cytokines (TNF-α, IL-6, IL-1β), and downregulates the levels of iNOS and COX-2. Chikusetsusaponin IVa methyl ester can be used in researches on colorectal cancer and inflammation .
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