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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
865 Results for "
Chloride
" in MedChemExpress (MCE) Product Catalog:
Products (865)
865 Results for "Chloride" in MCE Product Catalog:
97
Target:
88
82
82 Cited Publications
Cat. No.: HY-17577
CAS No.: 68030-18-2
Synonyms: Natural Yellow 18 Chloride hydrate
73
Research Areas:
Diphenyleneiodonium chloride is a NADPH oxidase (NOX) inhibitor and also functions as a TRPA1 activator with an EC50 of 1 to 3 μM. Diphenyleneiodonium chloride selectively inhibits intracellular reactive oxygen species.
68
68 Cited Publications
Cat. No.: HY-Y1269
CAS No.: 12125-02-9
68
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Target:
Research Areas:
Acridine Orange zinc chloride salt is a cell-permeable fluorescent nucleic acid dye and lysosomal probe with a pKa of 9.65. Acridine Orange zinc chloride salt enters cells via passive diffusion, is protonated and accumulates in acidic lysosomes, and forms aggregates at high concentrations, producing orange-red fluorescence; when the lysosomal proton gradient or membrane integrity is impaired, Acridine Orange zinc chloride salt is released into the cytoplasm, green fluorescence increases and red fluorescence decreases, so it can be used to monitor lysosomal acidification status and changes in membrane permeability. Acridine Orange zinc chloride salt binds to nucleic acids through intercalation or electrostatic interactions, exhibiting mainly green fluorescence when bound to double-stranded DNA and mainly red fluorescence when bound to RNA or single-stranded DNA, and can be used for nucleic acid staining and differential DNA/RNA detection. The Ex/Em of Acridine Orange zinc chloride salt monomer is approximately 492/525 nm; when bound to double-stranded DNA it is approximately 488/520-524 nm, and when bound to RNA or single-stranded DNA it is approximately 457/630-650 nm .
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33 Cited Publications
Category:
Alkaloids Neurological Disease Anti-aging Animal Pyridine Alkaloids Metabolic Disease Disease Research Fields
Target:
31
31 Cited Publications
Synonyms: Basic Blue 9; CI-52015; Methylthioninium Chloride
28
28 Cited Publications
Cat. No.: HY-D0958
CAS No.: 122965-43-9
Synonyms: Basic Blue 9 hydrate; CI-52015 hydrate; Methylthioninium Chloride hydrate
Research Areas:
Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .
27
23
23 Cited Publications
Synonyms: 1,2-Dioleoyl-3-trimethylammonium-propane Chloride
DOTAP (1,2-Dioleoyl-3-trimethylammonium-propane) chloride is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP chloride promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP chloride can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design .
20
Category:
Alkaloids Plant Metabolic Disease Chelidonium majus Extract Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Papaveraceae Extract
Target:
17
17 Cited Publications
Synonyms: Sanguinarin Chloride; Sanguinarium Chloride; Pseudochelerythrine Chloride
14
14 Cited Publications
Synonyms: 2,3,5-Triphenyltetrazolium Chloride; TPTZ; TTC
13
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
