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Cudrania tricuspidata

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (1) Bacterial (1) Bcl-2 Family (1) Caspase (1) Cholinesterase (ChE) (1) Drug Derivative (2) ERK (1) JNK (1) LDLR (1) NO Synthase (1) p38 MAPK (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (1)

Inhibitors & Agonists

Natural
Products

Art. -Nr.	Produktname	Target	Forschungsgebiete	Chemical Structure

HY-N0627

Kaempferol-7-O-β-D-glucopyranoside	LDLR	Others
Kaempferol-7-O-β-D-glucopyranoside is a flavonoid glycoside. Kaempferol-7-O-β-D-glucopyranoside exists in the root bark of Cudrania tricuspidata. Kaempferol-7-O-β-D-glucopyranoside inhibits Cu ²⁺-induced lipid peroxidation of low-density lipoprotein. Kaempferol-7-O-β-D-glucopyranoside possesses antioxidant activity and scavenges DPPH free radicals .

HY-N2693

6,8-Diprenylorobol	Apoptosis Reactive Oxygen Species (ROS) Caspase Akt ERK JNK p38 MAPK Bcl-2 Family	Cancer
6,8-Diprenylorobol, a prenylated isoflavone, is a nature product that could be isolated from the leaves of Cudrania tricuspidata. 6,8-Diprenylorobol antiproliferative effect and induces apoptosis through activation of p53 and generation of ROS .

HY-N3647

Cudraxanthone D	Others	Others
Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata .

HY-N10985

Xanthone V1a	Drug Derivative	Cancer
Xanthone V1a, a derivative of Xanthone (HY-N0126), is an antioxidant that can be found in the roots of Cudrania tricuspidata and twig extracts of Maclura fruticosa. Xanthone V1a exerts cytotoxic effects against colon, hepatocellular, and gastric carcinoma cells. Xanthone V1a exhibits scavenging activitys against DPPH and ABTS. Xanthone V1a can be used for the research of colon carcinoma, hepatocellular carcinoma, and gastric carcinoma .

HY-N12833

Dihydrokaempferol-3-O-β-D-glucoside	Cholinesterase (ChE)	Others
Dihydrokaempferol-3-O-β-D-glucoside (Compound 3) is a compound that can be isolated from the bark of Cudrania tricuspidata (Carr.) Bur. . Dihydrokaempferol-3-O-β-D-glucoside is an inhibitor of acetylcholinesterase (AChE) .

HY-N8477

Isolupalbigenin	NO Synthase	Inflammation/Immunology
Isolupalbigenin is an inhibitor of NO. Isolupalbigenin has anti-proliferative activity on HL-60 cells with an IC₅₀ of 5.1 μM .

HY-N8283

Euchrestaflavanone B	Others	Others
Euchrestaflavanone B is a Flavonoids product that can be isolated from the root barks of Cudrania tricuspidata. .

HY-N2692

6,8-Diprenylgenistein	Bacterial	Cancer
6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .

HY-N7380

Cudraxanthone B	Drug Derivative	Others
Cudraxanthone B is a natural xanthone.

Kaempferol-7-O-β-D-glucopyranoside	Flavonols Structural Classification Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	LDLR
Kaempferol-7-O-β-D-glucopyranoside is a flavonoid glycoside. Kaempferol-7-O-β-D-glucopyranoside exists in the root bark of Cudrania tricuspidata. Kaempferol-7-O-β-D-glucopyranoside inhibits Cu ²⁺-induced lipid peroxidation of low-density lipoprotein. Kaempferol-7-O-β-D-glucopyranoside possesses antioxidant activity and scavenges DPPH free radicals .

6,8-Diprenylorobol	Flavonoids Maclura tricuspidata Carriere Plants Moraceae Isoflavones Source Classification	Apoptosis Reactive Oxygen Species (ROS) Caspase Akt ERK JNK p38 MAPK Bcl-2 Family
6,8-Diprenylorobol, a prenylated isoflavone, is a nature product that could be isolated from the leaves of Cudrania tricuspidata. 6,8-Diprenylorobol antiproliferative effect and induces apoptosis through activation of p53 and generation of ROS .

Cudraxanthone D	Xanthones Maclura tricuspidata Carriere Phenols Plants Moraceae Source Classification	Others
Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata .

Xanthone V1a	Structural Classification Flavonoids Maclura fruticosa (Roxburgh) Corner Plants Moraceae Other Flavonoids Source Classification	Drug Derivative
Xanthone V1a, a derivative of Xanthone (HY-N0126), is an antioxidant that can be found in the roots of Cudrania tricuspidata and twig extracts of Maclura fruticosa. Xanthone V1a exerts cytotoxic effects against colon, hepatocellular, and gastric carcinoma cells. Xanthone V1a exhibits scavenging activitys against DPPH and ABTS. Xanthone V1a can be used for the research of colon carcinoma, hepatocellular carcinoma, and gastric carcinoma .

Dihydrokaempferol-3-O-β-D-glucoside	Structural Classification Flavanonols Flavonoids Flavonones Maclura tricuspidata Carriere Plants Moraceae Source Classification	Cholinesterase (ChE)
Dihydrokaempferol-3-O-β-D-glucoside (Compound 3) is a compound that can be isolated from the bark of Cudrania tricuspidata (Carr.) Bur. . Dihydrokaempferol-3-O-β-D-glucoside is an inhibitor of acetylcholinesterase (AChE) .

Isolupalbigenin	Flavonoids Maclura tricuspidata Carriere Plants Moraceae Isoflavones Source Classification	NO Synthase
Isolupalbigenin is an inhibitor of NO. Isolupalbigenin has anti-proliferative activity on HL-60 cells with an IC₅₀ of 5.1 μM .

Euchrestaflavanone B	Flavonoids Maclura tricuspidata Carriere Plants Moraceae Source Classification	Others
Euchrestaflavanone B is a Flavonoids product that can be isolated from the root barks of Cudrania tricuspidata. .

6,8-Diprenylgenistein	Structural Classification Flavonoids Leguminosae Phenols Polyphenols Plants Derris taiwaniana (Hayata) Z. Q. Song Isoflavones Source Classification	Bacterial
6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .

Cudraxanthone B	Structural Classification Maclura tricuspidata Carriere Phenols Polyphenols Plants Moraceae Source Classification	Drug Derivative
Cudraxanthone B is a natural xanthone.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Cudrania tricuspidata

Inhibitors & Agonists

NaturalProducts

Natural
Products