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Cat. No.: HY-N2692

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6,8-Diprenylgenistein

6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .

For research use only. We do not sell to patients.

CAS No.: 51225-28-6
Formula: C₂₅H₂₆O₅
Molecular Weight:406.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

6,8-Diprenylgenistein Chemical Structure

CAS No.: 51225-28-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
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Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	8.58 μM Compound: 38	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay	[PMID: 28522265]
RAW264.7	IC₅₀	19.2 μM Compound: 10	Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess assay Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess assay	[PMID: 19113968]
SW480	IC₅₀	8.08 μM Compound: 38	Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay	[PMID: 28522265]

Chemical Information

CAS No. 51225-28-6
Molecular Weight 406.47
Formula C₂₅H₂₆O₅
SMILES

O=C1C(C2=CC=C(O)C=C2)=COC3=C(C/C=C(C)\C)C(O)=C(C/C=C(C)\C)C(O)=C13
Structure Classification
- Flavonoids
- Isoflavones
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bae MG, et al. Effects of 6,8-Diprenylgenistein on VEGF-A-Induced Lymphangiogenesis and Lymph Node Metastasis in an Oral Cancer Sentinel Lymph Node Animal Model. Int J Mol Sci. 2021 Jan 14;22(2):770. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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