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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
Cytostatic
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "Cytostatic" in MCE Product Catalog:
11
Target:
Domaines de recherche:
Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of ATP: L-methionine-S-adenosyl transferase in vitro. Cycloleucine has anxiolytic and cytostatic effects .
5
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Carboxyamidotriazole (L-651582) is an orally active cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole inhibits NF-κB, MAPK activation and NO production. Carboxyamidotriazole has anti-angiogenic and anti-inflammatory activities. Carboxyamidotriazole has anticancer activity against liver cancer, lung cancer and leukemia .
5
5 Cited Publications
Cat. No.: HY-16125
CAS No.: 187739-60-2
Synonyms: L-651582 Orotate; CAI Orotate
Target:
Domaines de recherche:
Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate shows anti-tumor, anti-inflammatory and antiangiogenic effects .
3
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Mitonafide (NSC 300288) is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia .
2
2 Cited Publications
Cat. No.: HY-N0526
CAS No.: 53209-27-1
Domaines de recherche:
Tezacitabine is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue. Tezacitabine irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine effectively induces cells apoptotic. Tezacitabine has the potential for leukemias and solid tumors (carcinomas) treatment .
Cat. No.: HY-125539
CAS No.: 16891-85-3
Category:
Target:
Cat. No.: HY-W010417
CAS No.: 591-28-6
Target:
Domaines de recherche:
4-Thiouracil is a thionucleobase with cytostatic properties. 4-Thiouracil can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts. 4-Thiouracil can also act as a strong ultraviolet A (UVA) photosensitizer, providing a source of the reactive oxygen species of O2. 4-Thiouracil is promising for research of photocross linking, photodamage, as well as photodynamic therapy .
Cat. No.: HY-15266
CAS No.: 112827-99-3
Synonyms: PRI 2202; Impurity D of Calcipotriol
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Domaines de recherche:
24R-Calcipotriol (PRI 2202; Impurity D of Calcipotriol), an isomer of Calcipotriol (HY-10001), is a synthetic vitamin D analog. 24R-Calcipotriol exhibits synergistic antiproliferative effects with low-dose cytostatics in in vitro. 24R-Calcipotriol produces tumor growth inhibition when combined with Cyclophosphamide (HY-17420) and Cisplatin (HY-17394) in mice models. 24R-Calcipotriol can increase serum calcium levels and reduce blood leukocyte counts . 24R-Calcipotriol can be used for the research of mammary cancer and Lewis lung cancer .
Cat. No.: HY-W014674
CAS No.: 6575-24-2
Target:
Domaines de recherche:
2,6-Dichlorophenylacetic acid is an inhibitor of isopenicillin N synthase (IPNS) and acyl-CoA: 6-APA acyltransferase. 2,6-Dichlorophenylacetic acid is also part of a group of phenylacetate derivatives that have cytostatic activity against tumour cells .
Cat. No.: HY-128747R
CAS No.: 56401-20-8
Domaines de recherche:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
α-D-Glucose-1-phosphate disodium (Standard) is the analytical standard of α-D-Glucose-1-phosphate disodium (HY-128747). This product is intended for research and analytical applications.
α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element.
Cat. No.: HY-W400427
CAS No.: 59-56-3
Domaines de recherche:
α-D-Glucose-1-phosphate is a derivative of D-glucose (HY-B0389). α-D-Glucose-1-phosphate serves as a starting material for glucuronic acid synthesis. Glucuronic acid acts as a Ca 2+ chelator and also functions as a biosynthetic substrate for the production of linear maltooligosaccharides or α,α-trehalose. α-D-Glucose-1-phosphate can be used as a cytostatic compound, Antibiotic, and immunosuppressant essential for heart disease management. α-D-Glucose-1-phosphate is applicable to the research of heart disease .
Cat. No.: HY-N12396
CAS No.: 108027-45-8
Category:
Target:
Target:
Domaines de recherche:
Ypenyl is a cytostatic. Ypenyl hydrochloride, belonging to the alkylating agent class, exhibits clear genotoxicity and cell cycle disruption properties. Ypenyl induces chromosomal aberrations in broad bean root tip meristem cells and leads to a decrease in the mitotic index. Ypenyl may be used in cancer research .
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Domaines de recherche:
Acid Ceramidase-IN-2 (compound 1) is an acid ceramidase inhibitor with potentially antiproliferative and cytostatic activities. Moreover, human acid ceramidase is overexpressed in prostate cancer cells, indicating potential anti-tumor effect of Acid Ceramidase-IN-2. And Acid Ceramidase-IN-2 hydrolysis can be inhibited by 3 a-ketoamides GT85, GT98 and GT99 inhibits in vitro .
Cat. No.: HY-116280
CAS No.: 133084-09-0
Category:
Monophenols Elaeocarpaceae Phenols Plants Aceratium megalospermum (F.Muell.) Balgooy Saccharides Monosaccharides
Target:
Cat. No.: HY-115761
CAS No.: 52574-64-8
Dihydrochlamydocin is a histone deacetylases (HDAC) inhibitor. Dihydrochlamydocin shows strong cytostatic activity towards mastocytoma cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
