Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Dichlorodiphenyltrichloroethane
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Dichlorodiphenyltrichloroethane" in MCE Product Catalog:
6
6 Cited Publications
Synonyms: 2,4′-DDD; o,p'-DDD
Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
1
1 Cited Publications
Cat. No.: HY-P10579
CAS No.: 2225868-19-7
Target:
Research Areas:
Cat. No.: HY-P10563
CAS No.: 2580150-96-3
Synonyms: BHV-1100
Cat. No.: HY-B1986S
CAS No.: 93952-19-3
Synonyms: 4,4'-DDE-d8; p,p'-Dichlorodiphenyldichloroethylene-d8
Cat. No.: HY-P3350
CAS No.: 2892148-58-0
Target:
Research Areas:
Mitotane (Standard) is the analytical standard of Mitotane. This product is intended for research and analytical applications. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
Synonyms: 2,4′-DDD-13C6; o,p'-DDD-13C6
Cat. No.: HY-13690S3
CAS No.: 2483736-36-1
Synonyms: 2,4′-DDD-13C12; o,p'-DDD-13C12
Cat. No.: HY-105168
CAS No.: 157380-72-8
Target:
Research Areas:
Cat. No.: HY-W753141
CAS No.: 201612-50-2
Synonyms: 4,4'-DDE-13C12; p,p'-Dichlorodiphenyldichloroethylene-13C12
Cat. No.: HY-13690S2
CAS No.: 2673270-14-7
Synonyms: 2,4′-DDD-d8; o,p'-DDD-d8
Cat. No.: HY-P1981
CAS No.: 157381-54-9
Target:
Research Areas:
Rpi-856 A is a competitive inhibitor of HIV-1 protease and HTLV-I protease, with an IC50 of 37 nM against HIV-1 protease and an IC50 of 27 nM against HTLV-I protease. Rpi-856 A inhibits Pepsin with an IC50 of 1.9 μM . Rpi-856 A does not inhibit chymosin, trypsin, chymotrypsin, papain, bromelain, thermolysin, prolyl endopeptidase, carboxypeptidase A or carboxypeptidase B. Rpi-856 A can be used in the research of acquired immunodeficiency syndrome (AIDS) and related diseases, as well as HIV infection .
Cat. No.: HY-P1982
CAS No.: 157381-55-0
Research Areas:
Rpi-856 C is an Aspartic protease inhibitor, with an IC50 of 5.5 nM against HIV-1 protease, 9.2 nM against HTLV-I protease, 2.0 μM against Cathepsin D, and 4.8 μM against Pepsin. Rpi-856 C is produced by the Streptomyces strain AL-322. Rpi-856 C does not inhibit chymosin, trypsin, chymotrypsin, papain, bromelain, thermolysin, prolyl endopeptidase, carboxypeptidase A or carboxypeptidase B. Rpi-856 C can be used in the research of acquired immunodeficiency syndrome (AIDS) and related diseases, as well as HIV infection .
Cat. No.: HY-P4948
CAS No.: 1926163-49-6
Target:
Research Areas:
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
