1 Result for "

Diflapolin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Diflapolin" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-128171
CAS No.: 724453-98-9
Purity:  99.67%
Target:  

FLAP Epoxide Hydrolase

Research Areas:  

Inflammation/Immunology

Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity. Diflapolin inhibits 5-LOX product formation in intact human monocytes and neutrophils with IC50s?of? 30 and 170?nM, respectively, and suppressed the activity of isolated sEH (IC50=20?nM) .
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