1 Result for "

Dihydroxy Oxaliplatin-Pt(IV)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Dihydroxy Oxaliplatin-Pt(IV)" in MCE Product Catalog:

Cat. No.: HY-W778423
CAS No.: 111321-67-6
Synonyms: Dihydroxy Oxaliplatin-Pt(IV)
Target:  

Drug Intermediate

Research Areas:  

Cancer

[Pt(DACH)(OH)2(ox)] is a Pt(IV) derivative of Oxaliplatin (HY-17371) with two axial hydroxido ligands, used as a precursor for synthesizing Pt(IV)-HDAC inhibitor prodrugs. [Pt(DACH)(OH)2(ox)] exerts cytotoxic activity against human cancer cells and accumulates in cancer cells for nuclear internalization and nuclear DNA platination. [Pt(DACH)(OH)2(ox)] can be used for the research of lung carcinoma, breast carcinoma, pancreatic carcinoma, colon carcinoma .
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