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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Dolutegravir sodium
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Dolutegravir sodium" in MCE Product Catalog:
37
37 Cited Publications
Synonyms: S/GSK1349572 sodium
Target:
Research Areas:
Dolutegravir sodium (S/GSK1349572 sodium) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir sodium (S/GSK1349572 sodium) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir sodium (S/GSK1349572 sodium) retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM) .
37
37 Cited Publications
Synonyms: S/GSK1349572
Target:
Research Areas:
Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM) .
Target:
Research Areas:
Dolutegravir intermediate-1 (Compound 11) is a synthetic intermediate. Dolutegravir intermediate-1 can be used to synthesize Dolutegravir (HY-13238). Dolutegravir is an Integrase inhibitor with potential applications in HIV-1 infection research .
Cat. No.: HY-138011
CAS No.: 1485692-21-4
Synonyms: Dolutegravir glucuronide; DTG glucuronide
Target:
Research Areas:
Dolutegravir O-β-D-glucuronide (Dolutegravir glucuronide) is a compound used for the simultaneous determination of rilpivirine and dolutegravir concentrations in human plasma.
Cat. No.: HY-13238R
CAS No.: 1051375-16-6
Synonyms: S/GSK1349572 (Standard)
Target:
Research Areas:
Dolutegravir (Standard) is the analytical standard of Dolutegravir. This product is intended for research and analytical applications. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM) .
Synonyms: S/GSK1349572-d3
Cat. No.: HY-13238S2
CAS No.: 2249814-82-0
Synonyms: S/GSK1349572-d5
Cat. No.: HY-W749636
CAS No.: 1485081-26-2
Target:
Research Areas:
N-De-2,4-difluorobenzyl dolutegravir is a metabolite of Dolutegravir (HY-13238). Dolutegravir is a HIV integrase inhibitor inhibitor .
Cat. No.: HY-100083R
CAS No.: 1335210-23-5
Target:
Research Areas:
Dolutegravir intermediate-1 (Standard) is the analytical standard of Dolutegravir intermediate-1 (HY-100083). This product is intended for research and analytical applications. Dolutegravir intermediate-1 is a synthetic intermediate of Dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
Cat. No.: HY-W781966
CAS No.: 1357289-37-2
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Research Areas:
4-epi-Dolutegravir (compound H3) is the (4S, 12aS) diastereomer of Dolutegravir (HY-13238), and also a hydrolytic degradation product of a HIV integrase inhibitor .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
