4-epi-Dolutegravir
Based on 1 Customer Validation
4-epi-Dolutegravir (compound H3) is the (4S, 12aS) diastereomer of Dolutegravir (HY-13238), and also a hydrolytic degradation product of a HIV integrase inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 1357289-37-2
- Formula: C20H19F2N3O5
- Molecular Weight:419.38
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 1357289-37-2
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Appearance Solid
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Molecular Weight 419.38
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Formula C20H19F2N3O5
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SMILES
O=C(NCC1=CC=C(C=C1F)F)C2=CN(C[C@@]3(OCC[C@@H](N3C4=O)C)[H])C4=C(C2=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 30 mg/mL (71.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3845 mL | 11.9224 mL | 23.8447 mL | 59.6118 mL |
| 5 mM | 0.4769 mL | 2.3845 mL | 4.7689 mL | 11.9224 mL | |
| 10 mM | 0.2384 mL | 1.1922 mL | 2.3845 mL | 5.9612 mL | |
| 15 mM | 0.1590 mL | 0.7948 mL | 1.5896 mL | 3.9741 mL | |
| 20 mM | 0.1192 mL | 0.5961 mL | 1.1922 mL | 2.9806 mL | |
| 25 mM | 0.0954 mL | 0.4769 mL | 0.9538 mL | 2.3845 mL | |
| 30 mM | 0.0795 mL | 0.3974 mL | 0.7948 mL | 1.9871 mL | |
| 40 mM | 0.0596 mL | 0.2981 mL | 0.5961 mL | 1.4903 mL | |
| 50 mM | 0.0477 mL | 0.2384 mL | 0.4769 mL | 1.1922 mL | |
| 60 mM | 0.0397 mL | 0.1987 mL | 0.3974 mL | 0.9935 mL |