1 Result for "

EF1500

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EF1500" in MCE Product Catalog:

Cat. No.: HY-189042
CAS No.: 738562-57-7
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

EF1500 is a potent human GABA transporter 1 (hGAT1) inhibitor and a lipophilic THPO analog. EF1500 occupies the binding site by forming a hydrogen bond with active residues of hGAT1 (such as Tyr139) through its exocyclic amino group, thereby blocking GABA reuptake. EF1500 can be used for research on central nervous system diseases .
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