2 Results for "

EGFR-IN-216

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "EGFR-IN-216" in MCE Product Catalog:

Cat. No.: HY-187334
CAS No.: 1923767-20-7
Target:  

EGFR Bcr-Abl Apoptosis

Research Areas:  

Cancer

EGFR-IN-216 is an epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor. EGFR-IN-216 inhibits EGFR tyrosine kinase phosphorylation, blocks downstream signaling pathway activation, suppresses cancer cell proliferation and promotes tumor cell apoptosis (apoptosis). EGFR-IN-216 can be used for the research of non-small cell lung cancer .
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Cat. No.: HY-156872
CAS No.: 1952236-19-9
Target:  

PI3K EGFR Syk Apoptosis

Research Areas:  

Cancer

MTX-216 is a dual ATP-competitive inhibitor of PI3K and EGFR. MTX-216 cosuppresses Ki-67 and ribosomal S6 phosphorylation and induces apoptosis in NF1 LOF cells. MTX-216 suppresses the activity of SYK kinase, with an IC50 of 281 nM. MTX-216 is used in the research of Melanoma .
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