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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Endothelium-denuded rings
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Endothelium-denuded rings" in MCE Product Catalog:
Cat. No.: HY-W507009
CAS No.: 40968-45-4
Target:
Research Areas:
L-Arginyl-L-alanine is a dipeptide, is a vascular smooth muscle-derived relaxing factor. L-Arginyl-L-alanine increases the smooth muscle levels of cyclic GMP and nitrite in endothelium-denuded arterial rings .
Cat. No.: HY-W047432
CAS No.: 90348-29-1
Synonyms: DL0805
Target:
Research Areas:
5-Nitro-1H-indazole-3-carbonitrile (DL0805) is a Rho kinase(ROCK) inhibitor with an IC50 of 6.67 μM for ROCK-I. 5-Nitro-1H-indazole-3-carbonitrile reduces Norepinephrine (HY-13715)-induced transient contraction and inhibits contraction induced by increasing external calcium in the endothelium-denuded rings of rat models. 5-Nitro-1H-indazole-3-carbonitrile has a vasorelaxant activity but high toxicity. 5-Nitro-1H-indazole-3-carbonitrile can be used for cardiovascular diseases, especially hypertension research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
