Search Result

Results for "

Fritillaria

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bcl-2 Family (1) Caspase (1) Cholinesterase (ChE) (2) Drug Derivative (1) Interleukin Related (1) mAChR (1) MyD88 (1) nAChR (1) NF-κB (1) p38 MAPK (1) TNF Receptor (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (2) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107277

Hapepunine	Others	Others
Hapepunine is a N-methyl-22,26-epiminochole stene, that can be isaolated from the aerial parts of Fritillaria camtschatcensis .

HY-107275

Ebeiedinone	Cholinesterase (ChE)	Neurological Disease
Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase (ChE) at the concentration of 0.1 mM, with the inhibitory effects of 69.0% .

HY-N2637

Yibeinoside A	Others	Others
Yibeinoside A is an alkaloid isolated from the bulb of Fritillaria pallidiflora Schreb .

HY-N7600

Zhebeirine 25-Epieduardine; Puqiedinone	Others	Others
Zhebeirine (Puqiedinone), a steroidal alkaloid, is isolated from the bulbs of Fritillaria puqiensis. Zhebeirine exhibits antitussive and expectorant properties .

HY-121631

Yibeissine	Others	Others
Yibeissine is a steroidal alkaloid isolated from the bulb of Fritillaria pallioiflora Schren .

HY-N7596

Isoverticine	Others	Cancer
Isoverticine, a bioactive isosteroidal alkaloid isolated from bulbus of Fritillaria pallidiflora, displays significant cytotoxicity .

HY-N5104

Clemaphenol A	Others	Others
Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora .

HY-N12123

Peimisine 3-O-β-D-glucopyranoside	Others	Others
Peimisine 3-O-β-D-glucopyranoside (Compound 1) is a steroid alkaloid. Peimisine 3-O-β-D-glucopyranoside can be isolated and purified from natural Fritillaria unibracteata. Peimisine 3-O-β-D-glucopyranoside shows moderate protective effect on rotenone-induced neurotoxicity of PC12 cell line .

HY-N18296

Karelinine	Drug Derivative	Others
Karelinine is a steroidal alkaloid found in the bulbs of Fritillaria ussuriensis Maxim and Fritillaria karelinii. Karelinine shows accelerated absorption and elimination rates, and increased area under the curve (AUC_0-t) when administered as part of the nanodispersion preparation (FUN) in rat plasma following oral administration .

HY-N18163

Veratradiene A	Others	Others
Veratradiene A is an isosteroidal alkaloid found in the bulbs of Fritillaria verticillata Willd .

HY-N17849

Frititorine A	nAChR mAChR	Inflammation/Immunology
Frititorine A is a steroidal alkaloid that exists in the bulbs of Fritillaria tortifolia. Frititorine A exerts a relaxing effect on acetylcholine-induced tracheal contraction. Frititorine A can be used in asthma-related research .

HY-N7920

Protobioside	Others	Cancer
Protobioside is a steroidal saponin found in the dry bulbs of Fritillaria pallidiflora Schrenk. Protobioside shows no significant cytotoxic activity against human cancer cells .

HY-107272

Chuanbeinone 22-Epidelavinone	Cholinesterase (ChE) Apoptosis Bcl-2 Family Caspase Interleukin Related TNF Receptor Toll-like Receptor (TLR) MyD88 NF-κB p38 MAPK	Inflammation/Immunology Cancer
Chuanbeinone (22-Epidelavinone) is an orally active alkaloid found in Fritillaria pallidiflora. Chuanbeinone shows cytotoxicity against mutiple cancer cells and can induces apoptosis and S phase arrest. Chuanbeinone downregulates Bcl-2, upregulates Bax, and activates caspase-3. Chuanbeinone exerts anti-inflammatory and antitussive effects by reducing pro-inflammatory cytokine (IL-1β, IL-6 and TNF-α) production and mRNA expression, and inhibiting TRIF-, MyD88-, NF-κB-, and MAPK-dependent signaling pathways. Chuanbeinone inhibits AChE and BChE with IC₅₀ values of 7.7 and 0.7 μM. Chuanbeinone can be used for the researches of lung carcinoma, cough, inflammatory diseases .

Hapepunine	Alkaloids Liliaceae Other Alkaloids Fritillaria camschatcensis (L.) Ker Gawl. Plants Source Classification	Others
Hapepunine is a N-methyl-22,26-epiminochole stene, that can be isaolated from the aerial parts of Fritillaria camtschatcensis .

Ebeiedinone	Alkaloids Piperidine Alkaloids Liliaceae Plants Fritillaria ussuriensis Maxim. Source Classification	Cholinesterase (ChE)
Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase (ChE) at the concentration of 0.1 mM, with the inhibitory effects of 69.0% .

Yibeinoside A	Alkaloids other families Classification of Application Fields Other Diseases Plants Isoquinoline Alkaloids Disease Research Fields Source Classification	Others
Yibeinoside A is an alkaloid isolated from the bulb of Fritillaria pallidiflora Schreb .

Zhebeirine 25-Epieduardine; Puqiedinone	Fritillaria puqiensis G.D.Yu et G.Y. Chen Alkaloids Piperidine Alkaloids Liliaceae Classification of Application Fields Other Diseases Plants Disease Research Fields Steroids Source Classification	Others
Zhebeirine (Puqiedinone), a steroidal alkaloid, is isolated from the bulbs of Fritillaria puqiensis. Zhebeirine exhibits antitussive and expectorant properties .

Yibeissine	Liliaceae Classification of Application Fields Other Diseases Plants Disease Research Fields Steroids Source Classification Fritillaria cirrhosa	Others
Yibeissine is a steroidal alkaloid isolated from the bulb of Fritillaria pallioiflora Schren .

Isoverticine	Alkaloids Piperidine Alkaloids Fritillaria monantha Migo Liliaceae Classification of Application Fields Fritillaria pallidiflora Schrenk ex Fisch. & C. A. Mey. Plants Disease Research Fields Steroids Source Classification Cancer	Others
Isoverticine, a bioactive isosteroidal alkaloid isolated from bulbus of Fritillaria pallidiflora, displays significant cytotoxicity .

Clemaphenol A	Melia azedarach Linn. Classification of Application Fields Lignans Other Diseases Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Meliaceae Source Classification	Others
Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora .

Peimisine 3-O-β-D-glucopyranoside	Alkaloids Liliaceae Other Alkaloids Plants Fritillaria unibracteata Hsiao et K. C. Hsia Source Classification	Others
Peimisine 3-O-β-D-glucopyranoside (Compound 1) is a steroid alkaloid. Peimisine 3-O-β-D-glucopyranoside can be isolated and purified from natural Fritillaria unibracteata. Peimisine 3-O-β-D-glucopyranoside shows moderate protective effect on rotenone-induced neurotoxicity of PC12 cell line .

Karelinine	Structural Classification Liliaceae Fritillaria ussuriensis Maxim. Plants Steroids Source Classification	Drug Derivative
Karelinine is a steroidal alkaloid found in the bulbs of Fritillaria ussuriensis Maxim and Fritillaria karelinii. Karelinine shows accelerated absorption and elimination rates, and increased area under the curve (AUC_0-t) when administered as part of the nanodispersion preparation (FUN) in rat plasma following oral administration .

Veratradiene A	Structural Classification Alkaloids Piperidine Alkaloids Fritillaria verticillata Willd. Liliaceae Plants Source Classification	Others
Veratradiene A is an isosteroidal alkaloid found in the bulbs of Fritillaria verticillata Willd .

Frititorine A	Structural Classification Alkaloids Liliaceae Other Alkaloids Plants AFritillaria tortifolia X. Z. Duan & X. J. Zheng Source Classification	nAChR mAChR
Frititorine A is a steroidal alkaloid that exists in the bulbs of Fritillaria tortifolia. Frititorine A exerts a relaxing effect on acetylcholine-induced tracheal contraction. Frititorine A can be used in asthma-related research .

Protobioside	Structural Classification Liliaceae Fritillaria pallidiflora Schrenk ex Fisch. & C. A. Mey. Plants Steroids Source Classification	Others
Protobioside is a steroidal saponin found in the dry bulbs of Fritillaria pallidiflora Schrenk. Protobioside shows no significant cytotoxic activity against human cancer cells .

Chuanbeinone 22-Epidelavinone	Structural Classification Alkaloids Liliaceae Other Alkaloids Fritillaria pallidiflora Schrenk ex Fisch. & C. A. Mey. Plants Source Classification	Cholinesterase (ChE) Apoptosis Bcl-2 Family Caspase Interleukin Related TNF Receptor Toll-like Receptor (TLR) MyD88 NF-κB p38 MAPK
Chuanbeinone (22-Epidelavinone) is an orally active alkaloid found in Fritillaria pallidiflora. Chuanbeinone shows cytotoxicity against mutiple cancer cells and can induces apoptosis and S phase arrest. Chuanbeinone downregulates Bcl-2, upregulates Bax, and activates caspase-3. Chuanbeinone exerts anti-inflammatory and antitussive effects by reducing pro-inflammatory cytokine (IL-1β, IL-6 and TNF-α) production and mRNA expression, and inhibiting TRIF-, MyD88-, NF-κB-, and MAPK-dependent signaling pathways. Chuanbeinone inhibits AChE and BChE with IC₅₀ values of 7.7 and 0.7 μM. Chuanbeinone can be used for the researches of lung carcinoma, cough, inflammatory diseases .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
Email *

	Sorry, but the email address you supplied was invalid.

Fritillaria

Inhibitors & Agonists

NaturalProducts

Natural
Products